SLU7

Description		spliceosome associated SLU7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Intracellular Protein Transport RNA Splicing Cellular Response To Heat
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)
Novel Interacting Genes		2 novel interacting genes: ARHGEF5 FAM200C
Interacting Genes		29 interacting genes: AIMP2 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I HNRNPA0 IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIE PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZCCHC10
Entrez ID		10569
HPRD ID		12074
Ensembl ID		ENSG00000164609
Uniprot IDs		O95391
PDB IDs		5XJC 6ICZ 6QDV 7W5A 7W5B 8C6J 9FMD
Enriched GO Terms of Interacting Partners?		Nucleoplasm Peptidyl-prolyl Cis-trans Isomerase Activity Histone Methyltransferase Activity Histone H4R3 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein Demethylase Activity Cyclosporin A Binding Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Transcription Regulator Activator Activity Protein Binding Nucleus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization Protein Folding Histone Demethylase Activity Regulation Of Macromolecule Metabolic Process Regulation Of Protein Modification Process Chromatin Remodeling Histone Methyltransferase Complex Regulation Of Gene Expression Cytoskeleton Organization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Histone H2AR3 Methyltransferase Activity Primary Ureteric Bud Growth Coated Vesicle Membrane Positive Regulation Of Macromolecule Metabolic Process
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