SLU7 and BAG2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		SLU7	BAG2
Description		spliceosome associated SLU7	BAG cochaperone 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome	Cytosol Microtubule Axon Dendrite Protein Folding Chaperone Complex Dendritic Microtubule
	Molecular Function	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Transmembrane Transporter Binding Tau Protein Binding Protein-folding Chaperone Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Intracellular Protein Transport RNA Splicing Cellular Response To Heat	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Protein Stabilization Positive Regulation Of Proteasomal Protein Catabolic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)
Interacting Genes		29 interacting genes: AIMP2 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I HNRNPA0 IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIE PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZCCHC10	17 interacting genes: CCAR2 DAPK1 DISC1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83
Entrez ID		10569	9532
HPRD ID		12074	04859
Ensembl ID		ENSG00000164609	ENSG00000112208
Uniprot IDs		O95391	O95816
PDB IDs		5XJC 6ICZ 6QDV 7W5A 7W5B 8C6J 9FMD
Enriched GO Terms of Interacting Partners?		Nucleoplasm Peptidyl-prolyl Cis-trans Isomerase Activity Histone Methyltransferase Activity Histone H4R3 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein Demethylase Activity Cyclosporin A Binding Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Transcription Regulator Activator Activity Protein Binding Nucleus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization Protein Folding Histone Demethylase Activity Regulation Of Macromolecule Metabolic Process Regulation Of Protein Modification Process Chromatin Remodeling Histone Methyltransferase Complex Regulation Of Gene Expression Cytoskeleton Organization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Histone H2AR3 Methyltransferase Activity Primary Ureteric Bud Growth Coated Vesicle Membrane Positive Regulation Of Macromolecule Metabolic Process	C3HC4-type RING Finger Domain Binding Cytoplasm Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ATP-dependent Protein Folding Chaperone Nucleotide Binding ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Clathrin Coat Disassembly Positive Regulation Of Wnt Signaling Pathway Regulation Of Synaptic Vesicle Transport ATP Binding Protein Serine Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Stability Protein-containing Complex Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis MRNA Metabolic Process Spliceosomal Complex RNA Splicing Response To Stress Protein Serine/threonine Kinase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Heat Shock Protein Binding MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Oxidative Stress Protein Folding Regulation Of Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing Cellular Response To Stress Negative Regulation Of Autophagosome Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Response To Unfolded Protein Protein Kinase Activity Adenyl-nucleotide Exchange Factor Activity Mitochondrion Organization Cellular Response To Chemical Stress Regulation Of Cellular Response To Stress Intracellular Signal Transduction Syntaxin-1 Binding Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Ubiquitin Protein Ligase Binding
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