PPID and S100A2

Number of citations: 0 (PubMedID 20188096)
Data Source: BioGRID (pull down, affinity chromatography technology)

		PPID	S100A2
Name		peptidylprolyl isomerase D	S100 calcium binding protein A2
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cilium	None
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Isomerase Activity Nuclear Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Protein-containing Complex Assembly Cellular Response To UV-A	Endothelial Cell Migration
Pathways		ESR-mediated signaling	None
Drugs		None	Olopatadine Calcium Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
GWAS		Blood protein levels ( 30072576 ) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 ) Serum metabolite levels ( 23093944 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: LARP1	None recorded
Interacting Genes		20 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	16 interacting genes: ARL13B CEP20 EPO FAM209A FKBP4 MDM2 PPID S100A1 S100A3 S100B S100P STUB1 TP53 TPM1 TPM2 TPM3
Entrez ID		5481	6273
HPRD ID		11875	01508
Ensembl ID		ENSG00000171497	ENSG00000196754
Uniprot IDs		E5KN55 Q08752	P29034 Q5RHS7 R4GN49
PDB IDs		Not available	2RGI 4DUQ
GO Terms Enriched among Interactors		Identical Protein Binding Positive Regulation Of Nitric Oxide Biosynthetic Process Nitric-oxide Synthase Regulator Activity Protein Folding Chaperone Complex Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Metabolic Process Cytoplasm Response To Unfolded Protein Regulation Of Protein Import Cytosol MHC Class II Protein Complex Binding Protein Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process ATP-dependent Protein Folding Chaperone Positive Regulation Of Developmental Process Secretory Granule Lumen Ficolin-1-rich Granule Lumen Negative Regulation Of RNA Metabolic Process Regulation Of Viral Process Telomerase Holoenzyme Complex Assembly Protein-containing Complex Chaperone-mediated Autophagy Cellular Response To Heat Regulation Of Protein Localization To Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Dendritic Growth Cone TPR Domain Binding Regulation Of Cellular Component Organization Protein Folding Chaperone Positive Regulation Of Cell Differentiation Regulation Of Primary Metabolic Process Protein Modification Process Heat Shock Protein Binding Regulation Of Multicellular Organism Growth Regulation Of Protein Catabolic Process Regulation Of Protein Localization Regulation Of Protein Stability Protein Ubiquitination Regulation Of Biological Quality Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Calcium-dependent Protein Binding Regulation Of Metabolic Process	Muscle Thin Filament Tropomyosin Calcium-dependent Protein Binding Cellular Response To Actinomycin D Response To Hypoxia Response To Decreased Oxygen Levels Tau Protein Binding Response To Actinomycin D Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Cellular Response To UV-C Response To Oxygen Levels Cellular Response To Oxygen Levels Heat Shock Protein Binding Protein Homodimerization Activity Cellular Response To Antibiotic Regulation Of Blood Circulation Cellular Response To UV Response To UV-C Identical Protein Binding S100 Protein Binding Actin Filament Regulation Of System Process Response To Salt Stress Cellular Response To Light Stimulus Transition Metal Ion Binding Cytoplasm System Process Cytoskeleton Disordered Domain Specific Binding Cellular Response To Gamma Radiation Response To UV Cytosol Regulation Of ATP-dependent Activity Peptidyl-prolyl Cis-trans Isomerase Activity Cellular Response To Radiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Embryo Implantation Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Erythrocyte Apoptotic Process Steroid Hormone Receptor Complex Assembly Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Heart Contraction DNA Damage Response, Signal Transduction By P53 Class Mediator Supramolecular Fiber Organization Hsp90 Protein Binding Hsp70 Protein Binding Regulation Of Mitophagy