PPID and SLC25A4

Number of citations of the paper that reports this interaction (PubMedID 12149099)
35

Data Source:
HPRD (in vitro)

		PPID	SLC25A4
Description		peptidylprolyl isomerase D	solute carrier family 25 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cilium	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Isomerase Activity Nuclear Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Protein-containing Complex Assembly Cellular Response To UV-A	Generation Of Precursor Metabolites And Energy Apoptotic Mitochondrial Changes Adenine Transport ADP Transport Regulation Of Mitochondrial Membrane Permeability Transmembrane Transport Negative Regulation Of Necroptotic Process Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Adaptive Thermogenesis
Pathways		ESR-mediated signaling	Mitochondrial protein import Mitochondrial protein import Mitochondrial Uncoupling Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			ATP Clodronic acid Etidronic acid [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Tetrastearoyl cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Blood protein levels ( 30072576) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Serum metabolite levels ( 23093944)
Interacting Genes		20 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	7 interacting genes: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE
Entrez ID		5481	291
HPRD ID		11875	00058
Ensembl ID		ENSG00000171497	ENSG00000151729
Uniprot IDs		E5KN55 Q08752	A0A0S2Z3H3 P12235
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Positive Regulation Of Nitric Oxide Biosynthetic Process Nitric-oxide Synthase Regulator Activity Protein Folding Chaperone Complex Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Metabolic Process Cytoplasm Response To Unfolded Protein Regulation Of Protein Import Cytosol MHC Class II Protein Complex Binding Protein Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process ATP-dependent Protein Folding Chaperone Positive Regulation Of Developmental Process Secretory Granule Lumen Ficolin-1-rich Granule Lumen Negative Regulation Of RNA Metabolic Process Regulation Of Viral Process Telomerase Holoenzyme Complex Assembly Protein-containing Complex Chaperone-mediated Autophagy Cellular Response To Heat Regulation Of Protein Localization To Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Dendritic Growth Cone TPR Domain Binding Regulation Of Cellular Component Organization Protein Folding Chaperone Positive Regulation Of Cell Differentiation Regulation Of Primary Metabolic Process Protein Modification Process Heat Shock Protein Binding Regulation Of Multicellular Organism Growth Regulation Of Protein Catabolic Process Regulation Of Protein Localization Regulation Of Protein Stability Protein Ubiquitination Regulation Of Biological Quality Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Calcium-dependent Protein Binding Regulation Of Metabolic Process	Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Permeability Transition Pore Complex Estrogen Response Element Binding Apoptotic Process Programmed Cell Death Cell Death Cyclosporin A Binding Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Cellular Localization Steroid Binding Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Response To Ketone Intracellular Receptor Signaling Pathway Positive Regulation Of Membrane Permeability Peptidyl-prolyl Cis-trans Isomerase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Metabolic Process Regulation Of Transport Regulation Of Monoatomic Cation Transmembrane Transport Hsp90 Protein Binding Toll-like Receptor 4 Signaling Pathway Regulation Of Release Of Cytochrome C From Mitochondria Response To Lipid Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Hsp70 Protein Binding Nuclear Receptor Activity B Cell Receptor Signaling Pathway Cellular Response To Oxygen-containing Compound Cell Surface Pattern Recognition Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MiRNA Transcription Regulation Of Mitochondrial Membrane Permeability Regulation Of Protein Localization Lipid Binding Cellular Response To Hormone Stimulus Positive Regulation Of MiRNA Metabolic Process Immune Response-activating Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Mitochondrial Changes Enzyme Binding Prostate Induction Regulation Of Apoptotic Signaling Pathway Regulation Of MiRNA Transcription Regulation Of Intracellular Signal Transduction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?