WDR44 and RAB11A

Number of citations of the paper that reports this interaction (PMID 10464283)
23

Data Source:
HPRD (in vitro, in vivo)

		WDR44	RAB11A
Gene Name		WD repeat domain 44	RAB11A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Endosome Membrane Perinuclear Region Of Cytoplasm	Spindle Pole Mitochondrion Multivesicular Body Trans-Golgi Network Kinetochore Microtubule Cytosol Plasma Membrane Transport Vesicle Axon Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function		GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Syntaxin Binding Myosin V Binding
	Biological Process		Cytokinesis Renal Water Homeostasis Water Transport Intracellular Protein Transport Exocytosis Organelle Organization Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Transmembrane Transport Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Exosomal Secretion
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Vasopressin regulates renal water homeostasis via Aquaporins Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Aquaporin-mediated transport Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CSNK2A1 GRB2 RAB11A SEC13	28 interactors: CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB3IL1 RABGGTB RCHY1 SEC13 STX4 TBXA2R TDP2 WDR44 YWHAG
Entrez ID		54521	8766
HPRD ID		11682	05715
Ensembl ID		ENSG00000131725	ENSG00000103769
Uniprot IDs		Q5JSH3	P62491
PDB IDs			1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Positive Regulation Of Cell Growth Neuron Projection Development Multivesicular Body Assembly Regulation Of Multivesicular Body Size Neuron Development Protein Complex Assembly Multivesicular Body Organization Neuron Differentiation Establishment Of Vesicle Localization Cell Projection Organization Vesicle Localization Regulation Of Endosome Size Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Growth Regulation Of Cell Cycle Phase Transition Exosomal Secretion Cell Cycle Vesicle-mediated Transport Generation Of Neurons Establishment Of Organelle Localization Regulation Of Cellular Component Size Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Cell Growth Neurogenesis Axon Guidance Branching Involved In Labyrinthine Layer Morphogenesis Cell Development Regulation Of Mitotic Cell Cycle Organelle Localization Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Cell Cycle Process Axonogenesis COPII Vesicle Coating Mitotic Spindle Assembly Axon Development Nervous System Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis COPII-coated Vesicle Budding Labyrinthine Layer Morphogenesis Regulation Of Growth Small GTPase Mediated Signal Transduction Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Mitotic Metaphase Plate Congression	Protein Transport Establishment Of Protein Localization Protein Localization Establishment Of Localization In Cell Cellular Localization Organelle Localization Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Vesicle Localization Vesicle Localization Transport Exocytosis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Membrane Organization Intracellular Transport Regulation Of Signaling Golgi Vesicle Transport Cell Death Death Insulin Secretion Secretion By Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Synaptic Transmission Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulated Secretory Pathway Regulation Of Synaptic Plasticity Regulation Of Body Fluid Levels Amyloid Precursor Protein Catabolic Process Cell-cell Signaling Peptide Hormone Secretion Secretion Peptide Secretion Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway Signaling Apoptotic Process Cell Cycle Cell Communication Negative Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Cycle Process Negative Regulation Of Kinase Activity Hormone Secretion Regulation Of Protein Kinase Activity Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process
Tagcloud ?			c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Difference) ?			c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Intersection) ?