WDR44 and SEC13

Number of citations of the paper that reports this interaction (PMID 10747849)
4

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		WDR44	SEC13
Gene Name		WD repeat domain 44	SEC13 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Endosome Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Kinetochore Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Nuclear Pore Outer Ring Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process		Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating MRNA Transport Membrane Organization
Pathways			Mitotic Prometaphase Diseases of glycosylation Separation of Sister Chromatids Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Mitotic Anaphase Antigen Presentation: Folding, assembly and peptide loading of class I MHC M Phase Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Cell Cycle, Mitotic Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Resolution of Sister Chromatid Cohesion Defective ALG12 causes ALG12-CDG (CDG-1g) Mitotic Metaphase and Anaphase Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CSNK2A1 GRB2 RAB11A SEC13	8 interactors: CLDN12 EGFR NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44
Entrez ID		54521	6396
HPRD ID		11682	02538
Ensembl ID		ENSG00000131725	ENSG00000157020
Uniprot IDs		Q5JSH3	A8MWR8 B4DXJ1 P55735
PDB IDs			3BG0 3BG1
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Positive Regulation Of Cell Growth Neuron Projection Development Multivesicular Body Assembly Regulation Of Multivesicular Body Size Neuron Development Protein Complex Assembly Multivesicular Body Organization Neuron Differentiation Establishment Of Vesicle Localization Cell Projection Organization Vesicle Localization Regulation Of Endosome Size Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Growth Regulation Of Cell Cycle Phase Transition Exosomal Secretion Cell Cycle Vesicle-mediated Transport Generation Of Neurons Establishment Of Organelle Localization Regulation Of Cellular Component Size Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Cell Growth Neurogenesis Axon Guidance Branching Involved In Labyrinthine Layer Morphogenesis Cell Development Regulation Of Mitotic Cell Cycle Organelle Localization Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Cell Cycle Process Axonogenesis COPII Vesicle Coating Mitotic Spindle Assembly Axon Development Nervous System Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis COPII-coated Vesicle Budding Labyrinthine Layer Morphogenesis Regulation Of Growth Small GTPase Mediated Signal Transduction Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Mitotic Metaphase Plate Congression	Membrane Organization COPII Vesicle Coating COPII-coated Vesicle Budding Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Cytoplasmic Transport Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Cellular Component Assembly Protein Localization Establishment Of Organelle Localization Protein Complex Assembly Organelle Localization Cellular Localization Endomembrane System Organization Membrane Budding Alkanesulfonate Metabolic Process Regulation Of Multivesicular Body Size Multivesicular Body Assembly Cellular Protein Localization Protein Localization To Organelle ER To Golgi Vesicle-mediated Transport Protein Transport Response To Calcium Ion Intracellular Transport Protein Import Into Nucleus, Docking Multivesicular Body Organization Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Endosome Size Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Activation Of Phospholipase A2 Activity Exosomal Secretion Regulation Of Protein Localization Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Exit From Endoplasmic Reticulum Establishment Of Localization In Cell Vesicle Organization Response To Cobalamin Response To UV-A Regulation Of Protein Exit From Endoplasmic Reticulum Response To Hydroxyisoflavone Nuclear Pore Complex Assembly Establishment Of Protein Localization To Membrane
Tagcloud ?			antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Difference) ?			antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses
Tagcloud (Intersection) ?