NAB1

Description		NGFI-A binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Transcription Coregulator Activity
	Biological Process	Endochondral Ossification Regulation Of DNA-templated Transcription Schwann Cell Differentiation Myelination Regulation Of Epidermis Development Negative Regulation Of DNA-templated Transcription
Pathways		NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Autoimmune traits (pleiotropy) ( 30572963) Bone mineral density (Ward's triangle area) ( 27397699) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Multiple sclerosis ( 31604244) Polymyositis ( 26362759) Primary biliary cholangitis ( 26394269) Pulse pressure ( 27841878) Rheumatoid arthritis ( 30572963) Systemic lupus erythematosus ( 33536424) Systemic sclerosis ( 31672989) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		2 interacting genes: EGR1 POU2AF1
Entrez ID		4664
HPRD ID		02881
Ensembl ID		ENSG00000138386
Uniprot IDs		A8K8T1 B4DKG1 B8ZZS2 Q13506
PDB IDs		2YUF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Cellular Response To Mycophenolic Acid Glomerular Mesangial Cell Proliferation Cellular Response To Interleukin-8 Lymphocyte Differentiation Circadian Temperature Homeostasis Cellular Response To Heparin Regulation Of Progesterone Biosynthetic Process Mononuclear Cell Differentiation Hemi-methylated DNA-binding Leukocyte Differentiation POU Domain Binding Response To Heparin Double-stranded Methylated DNA Binding Lymphocyte Activation Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Cytokine Production Positive Regulation Of Cell Proliferation Involved In Kidney Development Leukocyte Activation Positive Regulation Of Hormone Biosynthetic Process Germinal Center B Cell Differentiation Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Estrous Cycle Locomotor Rhythm Cell Activation Positive Regulation Of Gene Expression Via Chromosomal CpG Island Demethylation Ovulation Cycle Regulation Of Cytokine Production Circadian Behavior Regulation Of Ketone Biosynthetic Process Regulation Of Hormone Biosynthetic Process Regulation Of Protein Sumoylation Rhythmic Behavior Histone Acetyltransferase Binding Interleukin-1-mediated Signaling Pathway Cellular Response To Gamma Radiation Mature B Cell Differentiation Involved In Immune Response Mature B Cell Differentiation Regulation Of Hormone Metabolic Process Temperature Homeostasis Positive Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Response To Gamma Radiation Positive Regulation Of MiRNA Transcription Skeletal Muscle Cell Differentiation Positive Regulation Of Interleukin-1 Beta Production Response To Ischemia
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