NAB1 and POU2AF1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		NAB1	POU2AF1
Gene Name		NGFI-A binding protein 1 (EGR1 binding protein 1)	POU class 2 associating factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Transcription Factor Binding	DNA Binding Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Endochondral Ossification Transcription, DNA-templated Regulation Of Transcription, DNA-templated Schwann Cell Differentiation Myelination Regulation Of Epidermis Development Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Humoral Immune Response
Pathways
Drugs
Diseases
GWAS			Corneal structure ( 23291589) Primary biliary cirrhosis ( 23000144)
Protein-Protein Interactions		2 interactors: EGR1 POU2AF1	16 interactors: GATA2 GTF2H1 GTF2I MSX2 NAB1 PAX8 POU2F1 POU2F2 RHOXF2 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK
Entrez ID		4664	5450
HPRD ID		02881	03126
Ensembl ID		ENSG00000138386	ENSG00000110777
Uniprot IDs		B8ZZS2 Q13506	Q16633
PDB IDs		2YUF	1CQT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Cellular Response To Mycophenolic Acid Response To Carbon Monoxide Positive Regulation Of Glomerular Mesangial Cell Proliferation Glomerular Mesangial Cell Proliferation Cellular Response To Heparin Cellular Response To Isoquinoline Alkaloid Positive Regulation Of Metanephric Glomerulus Development Response To Heparin Response To Norepinephrine Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Cellular Response To Hyperoxia Positive Regulation Of Glomerulus Development Cell Proliferation Involved In Kidney Development Cellular Response To Follicle-stimulating Hormone Stimulus Transcription From RNA Polymerase II Promoter Interleukin-1-mediated Signaling Pathway Cellular Response To Gamma Radiation Regulation Of Protein Sumoylation Cellular Response To Antibiotic Glomerulus Vasculature Development Response To Follicle-stimulating Hormone Cellular Response To Toxic Substance Cellular Response To Gonadotropin Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Response To Hyperoxia Response To Amphetamine Immune Response Positive Regulation Of Kidney Development Cellular Response To Alkaloid Response To Gonadotropin Response To Electrical Stimulus Cellular Response To CAMP Response To Cocaine Long-term Synaptic Potentiation Response To Amine Response To Gamma Radiation Cellular Response To Drug Regulation Of Neuronal Synaptic Plasticity Cellular Response To Interleukin-1 Cellular Response To Ionizing Radiation Response To Antibiotic Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Apoptotic Process Glomerulus Development Cellular Response To Mechanical Stimulus Positive Regulation Of Neuron Death BMP Signaling Pathway Oligodendrocyte Differentiation	Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Organ Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process Anatomical Structure Morphogenesis RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Cell Differentiation Ammonium Transport Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Quaternary Ammonium Group Transport Negative Regulation Of RNA Biosynthetic Process System Development Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Monoamine Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Stimulus Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Drug Transmembrane Transport Signal Transduction Involved In Regulation Of Gene Expression Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Secretion By Cell Organ Development Positive Regulation Of BMP Signaling Pathway Anatomical Structure Development Ammonium Transmembrane Transport
Tagcloud ?		acetylated actinomycin construct correlates downregulation egr egr3 h4 histones ifn ifngr ifngr1 ifns luc macrophage macrophages myeloid ngfi pol prevented promoter rapid reductions reflect repressive responsiveness silences silencing
Tagcloud (Difference) ?		acetylated actinomycin construct correlates downregulation egr egr3 h4 histones ifn ifngr ifngr1 ifns luc macrophage macrophages myeloid ngfi pol prevented promoter rapid reductions reflect repressive responsiveness silences silencing
Tagcloud (Intersection) ?