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TAS2R5 and CCL4
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TAS2R5
CCL4
Description
taste 2 receptor member 5
C-C motif chemokine ligand 4
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Extracellular Region
Extracellular Space
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
Taste Receptor Activity
Bitter Taste Receptor Activity
Cytokine Activity
Protein Binding
Chemokine Activity
CCR1 Chemokine Receptor Binding
CCR5 Chemokine Receptor Binding
Identical Protein Binding
CCR Chemokine Receptor Binding
Biological Process
Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Chemosensory Behavior
Sensory Perception Of Taste
Chemotaxis
Inflammatory Response
Immune Response
Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Signal Transduction
Cell-cell Signaling
Response To Virus
Response To Toxic Substance
Positive Regulation Of Cell Migration
Host-mediated Suppression Of Viral Transcription
Eosinophil Chemotaxis
Positive Regulation Of Calcium-mediated Signaling
Positive Regulation Of Calcium Ion Transport
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Sensory perception of sweet, bitter, and umami (glutamate) taste
Sensory perception of sweet, bitter, and umami (glutamate) taste
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Drugs
Diseases
GWAS
Anorexia nervosa (
23568457
)
Late-onset Alzheimer's disease (
27770636
)
Blood protein levels in cardiovascular risk (
28369058
)
Body mass index (
26426971
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
6 interacting genes:
CCL4
RTP2
SFT2D2
SLC30A2
TMEM187
VAMP5
26 interacting genes:
ACKR2
ARL13B
CCL3
CCR1
CCR3
CCR5
CCR8
CNR2
CXCL8
GJA8
GPR152
GPRC5D
MARCHF2
MRM1
SLC10A6
SLC18A1
SLC30A2
SLC30A8
SLC7A1
TAS2R5
TIMMDC1
TMEM14B
TMEM179B
TMEM31
TMEM86B
UNC93A
Entrez ID
54429
6351
HPRD ID
05453
01657
Ensembl ID
ENSG00000127366
ENSG00000275302
Uniprot IDs
A4D1U0
Q502V5
Q9NYW4
P13236
PDB IDs
1HUM
1HUN
1JE4
2FFK
2FIN
2X6L
3TN2
4RAL
Enriched GO Terms of Interacting Partners
?
Zinc Ion Import Into Zymogen Granule
Zinc Ion Import Into Mitochondrion
Zinc Ion Import Into Secretory Vesicle
CCR1 Chemokine Receptor Binding
Positive Regulation Of Natural Killer Cell Chemotaxis
Zinc:proton Antiporter Activity
Zinc Ion Import Into Lysosome
Zinc Export Across Plasma Membrane
Late Endosome
Establishment Of Protein Localization To Membrane
Olfactory Receptor Binding
CCR5 Chemokine Receptor Binding
Vacuolar Transmembrane Transport
Zinc Ion Import Into Organelle
Secretory Vesicle
Endomembrane System
Chemokine Receptor Activity
C-C Chemokine Binding
C-C Chemokine Receptor Activity
Cell Chemotaxis
Chemotaxis
Chemokine-mediated Signaling Pathway
Locomotion
G Protein-coupled Receptor Activity
Calcium-mediated Signaling
G Protein-coupled Receptor Signaling Pathway
Membrane
Plasma Membrane
Chemokine (C-C Motif) Ligand 5 Binding
Leukocyte Chemotaxis
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Migration
Immune Response
Inflammatory Response
Response To Cytokine
Response To Peptide
Zinc:proton Antiporter Activity
Cell Motility
Leukocyte Migration
Cytokine-mediated Signaling Pathway
Intracellular Signaling Cassette
Cellular Response To Cytokine Stimulus
Transport Vesicle Membrane
Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Zinc Ion Import Into Organelle
Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum
Monoatomic Cation Transport
Defense Response
External Side Of Plasma Membrane
Sarcoplasmic Reticulum Calcium Ion Transport
Dendritic Cell Chemotaxis
Metal Ion Transport
Transmembrane Transport
Response To Interleukin-1
Monoatomic Cation Transmembrane Transporter Activity
Import Into Cell
Negative Regulation Of Bone Mineralization
Positive Regulation Of Leukocyte Chemotaxis
Immune System Process
Monoatomic Ion Transport
Positive Regulation Of Neuroinflammatory Response
Secretory Granule Membrane
Monocyte Chemotaxis
Zinc Ion Transmembrane Transporter Activity
Dendritic Cell Migration
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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