CCL4 and SLC30A2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCL4	SLC30A2
Gene Name		chemokine (C-C motif) ligand 4	solute carrier family 30 (zinc transporter), member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Lysosomal Membrane Late Endosome Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding	Cation Transmembrane Transporter Activity
	Biological Process	Movement Of Cell Or Subcellular Component Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell-cell Signaling Response To Virus Response To Toxic Substance Negative Regulation By Host Of Viral Transcription Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Cell Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis	Zinc Ion Transport Transmembrane Transport Positive Regulation Of Sequestering Of Zinc Ion Cation Transmembrane Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Metal ion SLC transporters Zinc efflux and compartmentalization by the SLC30 family Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACKR2 CCL3 CCR1 CCR3 CCR5 CCR8 CXCL8 SLC30A2	6 interactors: ADAM33 CCDC155 CCL4 CCL4L2 PVR TNFRSF12A
Entrez ID		6351	7780
HPRD ID		01657	18057
Ensembl ID			ENSG00000158014
Uniprot IDs		P13236	B3KSN7 Q9BRI3
PDB IDs		1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Chemotaxis Response To Cytokine Positive Regulation Of Cytosolic Calcium Ion Concentration Inflammatory Response Cytokine-mediated Signaling Pathway Cytosolic Calcium Ion Homeostasis Locomotion Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Leukocyte Chemotaxis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Response To External Stimulus Cellular Ion Homeostasis Cellular Response To Organic Substance Cell Chemotaxis Metal Ion Homeostasis Cellular Chemical Homeostasis G-protein Coupled Receptor Signaling Pathway Ion Homeostasis Leukocyte Migration Immune Response Defense Response Cellular Homeostasis Response To Organic Substance Positive Regulation Of Leukocyte Chemotaxis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Leukocyte Migration Chemical Homeostasis Calcium-mediated Signaling Cell Surface Receptor Signaling Pathway Sarcoplasmic Reticulum Calcium Ion Transport Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Dendritic Cell Chemotaxis Regulation Of Chemotaxis Second-messenger-mediated Signaling Immune System Process Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Neutrophil Activation Regulation Of Ion Homeostasis Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Response To Cholesterol Regulation Of Behavior Dendritic Cell Migration	Cell Migration Cell Motility Locomotion Movement Of Cell Or Subcellular Component Chromosome Localization To Nuclear Envelope Involved In Synapsis Susceptibility To T Cell Mediated Cytotoxicity Substrate-dependent Cell Migration, Cell Attachment To Substrate Cell Chemotaxis Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Chemotaxis Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Virus Positive Regulation Of Immune Response To Tumor Cell Cell Adhesion Negative Regulation By Host Of Viral Transcription Inflammatory Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Negative Regulation Of Viral Transcription Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Calcium-mediated Signaling Response To External Stimulus Regulation Of Lymphocyte Migration Interaction With Symbiont Chemotaxis Substrate-dependent Cell Migration Positive Regulation Of Axon Extension Establishment Of Chromosome Localization Viral Entry Into Host Cell Regulation Of Calcium-mediated Signaling Entry Into Host Cell
Tagcloud ?		acetyltransferase boxes cat chloramphenicol coinciding construct constructs fibrogenesis fibrogenic fibrotic hepatic igfiir inducer latent livers m6p mannose mutagenized p75 participating participation quiescent reporter repressor residing stellate stimulant tetrachloride transcript
Tagcloud (Difference) ?		acetyltransferase boxes cat chloramphenicol coinciding construct constructs fibrogenesis fibrogenic fibrotic hepatic igfiir inducer latent livers m6p mannose mutagenized p75 participating participation quiescent reporter repressor residing stellate stimulant tetrachloride transcript
Tagcloud (Intersection) ?