TAS2R5 and TMEM187

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TAS2R5	TMEM187
Description		taste 2 receptor member 5	transmembrane protein 187
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane Transport Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity	Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Chemosensory Behavior Sensory Perception Of Taste
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Late-onset Alzheimer's disease ( 27770636)	Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338 26663301)
Interacting Genes		6 interacting genes: CCL4 RTP2 SFT2D2 SLC30A2 TMEM187 VAMP5	15 interacting genes: ADRB2 ARL13B CD79A CGRRF1 CISD2 COMT FAM210B GORAB LEUTX MUC1 PGRMC2 SAR1A SPAG4 TAS2R5 TMEM14B
Entrez ID		54429	8269
HPRD ID		05453	02086
Ensembl ID		ENSG00000127366	ENSG00000177854
Uniprot IDs		A4D1U0 Q502V5 Q9NYW4	Q14656
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle CCR1 Chemokine Receptor Binding Positive Regulation Of Natural Killer Cell Chemotaxis Zinc:proton Antiporter Activity Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Late Endosome Establishment Of Protein Localization To Membrane Olfactory Receptor Binding CCR5 Chemokine Receptor Binding Vacuolar Transmembrane Transport Zinc Ion Import Into Organelle Secretory Vesicle Endomembrane System
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