TAS2R5 and RTP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TAS2R5	RTP2
Description		taste 2 receptor member 5	receptor transporter protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Cell Surface Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Chemosensory Behavior Sensory Perception Of Taste	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane
Pathways		G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste	Expression and translocation of olfactory receptors
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Late-onset Alzheimer's disease ( 27770636)	Asthma ( 31959851) Basophil count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Skin pigmentation ( 28300201)
Interacting Genes		6 interacting genes: CCL4 RTP2 SFT2D2 SLC30A2 TMEM187 VAMP5	77 interacting genes: ABHD6 ANK1 ANKS6 AQP2 AQP6 ARL13B CD74 CD79A CISD2 CLDN7 CPLX4 CXorf66 EBP ELOVL4 ELOVL6 ELOVL7 ERGIC3 EVI2A EVI2B FAM174A FAM209A FAM210B FATE1 FFAR2 GET1 GJB1 GJB5 GPR101 GPR152 GPR42 GPX8 HIBADH HSD17B11 IFNGR2 JAGN1 KASH5 KCNJ6 KIR2DL3 LAMA4 LAPTM5 LEPROTL1 LIME1 MUC1 NDUFA7 NEMP1 PDZK1IP1 REEP4 RELL2 RNASEK SAR1A SCN3B SEC11C SGPL1 SLC10A1 SLC10A6 SLC14A1 SLC34A2 SLC35H1 SLC39A9 SLC61A1 SSMEM1 STOM STX1A STX2 TAS2R5 THAP4 TMEM267 TMEM31 TMEM35A TMEM51 TMEM52B TMEM86B TMEM92 TMPPE TMX2 UACA VMA21
Entrez ID		54429	344892
HPRD ID		05453	12371
Ensembl ID		ENSG00000127366	ENSG00000198471
Uniprot IDs		A4D1U0 Q502V5 Q9NYW4	Q5QGT7
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle CCR1 Chemokine Receptor Binding Positive Regulation Of Natural Killer Cell Chemotaxis Zinc:proton Antiporter Activity Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Late Endosome Establishment Of Protein Localization To Membrane Olfactory Receptor Binding CCR5 Chemokine Receptor Binding Vacuolar Transmembrane Transport Zinc Ion Import Into Organelle Secretory Vesicle Endomembrane System	Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Unsaturated Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Water Transport Bile Acid:sodium Symporter Activity Long-chain Fatty-acyl-CoA Metabolic Process Fatty-acyl-CoA Biosynthetic Process Transmembrane Transport Fluid Transport Very Long-chain Fatty Acid Metabolic Process Renal Water Transport
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