GDAP1 and TMEM218

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GDAP1	TMEM218
Description		ganglioside induced differentiation associated protein 1	transmembrane protein 218
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Cytosol Membrane	Cilium Membrane Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrial Fission Protein Targeting To Mitochondrion Mitochondrial Fusion Response To Retinoic Acid Cellular Response To Vitamin D
Pathways		Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Dysmenorrheic pain ( 27454463) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 32499647) Waist circumference ( 17903300)	Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		10 interacting genes: ABHD16A APOD CLCN7 DCBLD2 FAM114A1 PNLIPRP1 STARD4 TMEM14B TMEM218 TUBB	75 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FFAR2 FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 HSD17B13 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 MUC1 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR
Entrez ID		54332	219854
HPRD ID		05963	19054
Ensembl ID		ENSG00000104381	ENSG00000150433
Uniprot IDs		A0A6Q8PEZ4 A0A6Q8PH97 B4DIH2 Q8TB36	A2RU14 E9PI23
PDB IDs		7AIA 7ALM 7B2G 7Q6J 7Q6K 7YWD 8A4J 8A4K
Enriched GO Terms of Interacting Partners?		Acylglycerol Catabolic Process Cholesterol Binding Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Chloride:proton Antiporter Activity Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Lipid Transport Involved In Lipid Storage Cholesterol Transport Involved In Cholesterol Storage Positive Regulation Of Bile Acid Biosynthetic Process	Membrane Plasma Membrane Protein Binding Connexin Complex Regulation Of Myoblast Fusion Gap Junction Channel Activity Gap Junction Bile Acid:sodium Symporter Activity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fucose Binding Gap Junction-mediated Intercellular Transport Renal Water Transport Gap Junction Assembly Fatty Acid Elongation, Saturated Fatty Acid
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