POLG and SSBP1

Number of citations of the paper that reports this interaction (PMID 10827171)
35

Data Source:
HPRD (in vivo)

		POLG	SSBP1
Gene Name		polymerase (DNA directed), gamma	single-stranded DNA binding protein 1, mitochondrial
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Gamma DNA Polymerase Complex Mitochondrial Nucleoid Extracellular Vesicular Exosome	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome
	Molecular Function	Protease Binding DNA Binding Chromatin Binding DNA-directed DNA Polymerase Activity Exonuclease Activity Protein Binding	Chromatin Binding Single-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	DNA Metabolic Process DNA-dependent DNA Replication Mitochondrial DNA Replication Base-excision Repair, Gap-filling Aging DNA Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis	DNA Replication Organelle Organization Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis
Pathways			Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Height ( 18193045) Menopause (age at onset) ( 22267201)	Anorexia nervosa ( 23568457)
Protein-Protein Interactions		1 interactors: SSBP1	6 interactors: CDK1 CKS1B CKS2 LDB1 POLG YWHAQ
Entrez ID		5428	6742
HPRD ID		01438	02703
Ensembl ID		ENSG00000140521	ENSG00000106028
Uniprot IDs		E5KNU5 P54098	A4D1U3 B7Z268 Q04837
PDB IDs		3IKM	1S3O 2DUD 3ULL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis	Cell Division Histone H3-K4 Acetylation Pronuclear Fusion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Protein Kinase Activity G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Intracellular Transport Cell Cycle Process Regulation Of Protein Phosphorylation Base-excision Repair, Gap-filling Regulation Of Schwann Cell Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Protein Localization To Kinetochore Negative Regulation Of Erythrocyte Differentiation Aging Protein Localization To Chromosome, Centromeric Region Regulation Of Phosphorylation Positive Regulation Of Protein Import Into Nucleus, Translocation Mitochondrial DNA Replication Cell Cycle Organelle Organization Cerebellar Purkinje Cell Differentiation Histone Modification Regulation Of Phosphorus Metabolic Process Regulation Of Protein Import Into Nucleus, Translocation Cerebellar Purkinje Cell Layer Morphogenesis Mitotic G2 DNA Damage Checkpoint Regulation Of Intracellular Transport Ventricular Cardiac Muscle Cell Development Epithelial Structure Maintenance Mitochondrial DNA Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Tagcloud ?		aoa1 arsacs ataxia ataxias aved bewildering cag commoner concentrating covers drpla ea1 ea2 episodic expansions fragile friedreich neurologist permutation polyglutamine pretest probabilities profusion remainder scas telangiectasia tracts treatable tremor	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		aoa1 arsacs ataxia ataxias aved bewildering cag commoner concentrating covers drpla ea1 ea2 episodic expansions fragile friedreich neurologist permutation polyglutamine pretest probabilities profusion remainder scas telangiectasia tracts treatable tremor	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?