ADGRB1 and SNTB1

Number of citations of the paper that reports this interaction (PubMedID 23782696)
64

Data Source:
BioGRID (unspecified method)

		ADGRB1	SNTB1
Description		adhesion G protein-coupled receptor B1	syntrophin beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Extracellular Region Extracellular Space Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Membrane Cell Junction Dendrite Cell Projection Dendritic Spine Synapse Perinuclear Region Of Cytoplasm Anchoring Junction	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Protein-containing Complex Sarcolemma Synapse Anchoring Junction
	Molecular Function	Lipopolysaccharide Binding Phosphatidylserine Binding Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding PDZ Domain Binding
	Biological Process	Immune System Process Phagocytosis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Nervous System Development Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process	Muscle Contraction
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Bipolar disorder x sex interaction ( 34099189)	Apolipoprotein A1 levels ( 32203549) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Cerebrospinal T-tau levels ( 28247064) Eye morphology ( 29921221) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817 29083408) JT interval (sulfonylurea treatment interaction) ( 27958378) Myopia (pathological) ( 23406873) Myopia (severe) ( 23933737) Periodontitis (CDC/AAP) ( 24024966) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thalamus volume ( 31530798)
Interacting Genes		21 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 DRD2 ELMO1 ERBB2 GPR35 GPR37 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2	15 interacting genes: ABCA1 ACVR2B ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAPK12 RPS6KA1 SCN4A SCN5A UTRN VANGL2
Entrez ID		575	6641
HPRD ID		04062	02490
Ensembl ID		ENSG00000181790	ENSG00000172164
Uniprot IDs		A0A2R8Y5M7 O14514	Q13884
PDB IDs			7P70 7PC4
Enriched GO Terms of Interacting Partners?		PDZ Domain Binding Plasma Membrane Dystrophin-associated Glycoprotein Complex Protein Localization To Synapse Bicellular Tight Junction Anchoring Junction Protein Localization To Cell Junction Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Cell-cell Junction Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Synapse Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein-containing Complex Localization Neuromuscular Junction Adherens Junction Cell Junction L27 Domain Binding Beta-1 Adrenergic Receptor Binding Ionotropic Glutamate Receptor Binding Syntrophin Complex Sarcolemma Postsynaptic Density MPP7-DLG1-LIN7 Complex Neuroligin Family Protein Binding Membrane Protein Localization To Membrane Cytoplasm Establishment Or Maintenance Of Cell Polarity GMP Kinase Activity Structural Molecule Activity Synaptic Membrane Lateral Plasma Membrane Peristalsis GDP Metabolic Process Regulation Of Sodium Ion Transport Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Muscle Contraction Regulation Of Receptor Internalization Regulation Of Behavior Intracellular Protein Localization Protein Localization To Cell Periphery Regulation Of Membrane Potential Postsynaptic Membrane Presynapse Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Muscle Contraction Muscle System Process Plasma Membrane Sarcolemma Muscle Organ Development Muscle Structure Development Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Cell Communication Regulation Of Multicellular Organismal Process Lateral Plasma Membrane Regulation Of Sodium Ion Transport Vinculin Binding Striated Muscle Contraction Nitric-oxide Synthase Binding Voltage-gated Sodium Channel Complex Regulation Of Blood Circulation Regulation Of System Process Dystrophin-associated Glycoprotein Complex Regulation Of Striated Muscle Contraction Signal Transduction Cell-cell Signaling System Process Regulation Of Monoatomic Ion Transmembrane Transport Action Potential Regulation Of Skeletal Muscle Contraction Filopodium Membrane Voltage-gated Sodium Channel Activity Kinase Activity Signaling Establishment Of Planar Polarity Monoatomic Ion Channel Complex Synaptic Signaling Membrane Protein Serine/threonine/tyrosine Kinase Activity Phagocytosis, Engulfment Regulation Of Monoatomic Ion Transport Regulation Of Developmental Process Monoatomic Cation Channel Activity Regulation Of Muscle Contraction Sodium Channel Activity Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Developmental Process Regulation Of Biological Quality Regulation Of Heart Contraction Cardiac Muscle Contraction T-tubule ATP Binding Membrane Invagination Sphingolipid Floppase Activity
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