BAI1 and MAGI2

Number of citations of the paper that reports this interaction (PMID 23782696)
0

Data Source:
BioGRID (pull down)

		BAI1	MAGI2
Gene Name		brain-specific angiogenesis inhibitor 1	membrane associated guanylate kinase, WW and PDZ domain containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Integral Component Of Membrane	Nucleus Cytoplasm Late Endosome Plasma Membrane Tight Junction Postsynaptic Density Dendrite Slit Diaphragm Protein Complex Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	G-protein Coupled Receptor Activity	Signal Transducer Activity Protein Binding Phosphatase Binding Receptor Signaling Complex Scaffold Activity Beta-1 Adrenergic Receptor Binding SMAD Binding Type II Activin Receptor Binding
	Biological Process	Cell Adhesion Signal Transduction G-protein Coupled Receptor Signaling Pathway Axonogenesis Peripheral Nervous System Development Negative Regulation Of Cell Proliferation Negative Regulation Of Angiogenesis	Positive Regulation Of Receptor Internalization Planar Cell Polarity Pathway Involved In Axis Elongation Negative Regulation Of Cell Proliferation Positive Regulation Of Neuron Projection Development Cytoplasmic Transport Negative Regulation Of Cell Migration Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Activin Receptor Signaling Pathway Nerve Growth Factor Signaling Pathway Receptor Clustering Protein Heterooligomerization Negative Regulation Of Protein Kinase B Signaling SMAD Protein Signal Transduction Mitotic Cell Cycle Arrest Glomerular Visceral Epithelial Cell Development Cellular Response To Nerve Growth Factor Stimulus
Pathways			Nephrin interactions
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23007406) Hippocampal atrophy ( 19668339) Obesity-related traits ( 23251661) Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		16 interactors: BAIAP2 BAIAP3 DLG1 DLG4 INADL LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2	15 interactors: ACVR2A ADRB1 ARRDC3 ATN1 BAI1 CTNNB1 CTNND2 DLL1 DSCAML1 GRID2 PLXNB3 PTEN RAPGEF2 SMAD3 TGFA
Entrez ID		575	9863
HPRD ID		04062	16212
Ensembl ID		ENSG00000181790	ENSG00000187391
Uniprot IDs		O14514	Q86UL8
PDB IDs			1UEP 1UEQ 1UEW 1UJV 1WFV
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Clustering Nucleotide Phosphorylation Maintenance Of Apical/basal Cell Polarity Regulation Of Sodium Ion Transport Receptor Localization To Synapse Maintenance Of Cell Polarity Cellular Component Assembly Protein Localization To Membrane Protein Localization To Synapse Membrane Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Receptor Internalization Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Protein Kinase B Signaling Regulation Of Sodium Ion Transmembrane Transport Plasma Membrane Organization Muscle Contraction Regulation Of Ion Transport Tight Junction Assembly Muscle System Process Regulation Of Membrane Potential Regulation Of Vasoconstriction By Circulating Norepinephrine Signaling Cell Communication Apical Junction Assembly Regulation Of Actin Filament-based Process Planar Cell Polarity Pathway Involved In Axis Elongation Cell-cell Signaling Negative Regulation Of Intracellular Signal Transduction Regulation Of Ion Transmembrane Transport Endomembrane System Organization Synaptic Vesicle Transport Neurotransmitter Secretion Regulation Of Intracellular Signal Transduction Protein Complex Assembly Cell-cell Junction Assembly Regulation Of Protein Kinase B Signaling Secretion By Cell Dendrite Development Axonogenesis Regulation Of Neurotransmitter Levels Nephron Development Protein Localization To Basolateral Plasma Membrane Negative Regulation Of Peptidyl-cysteine S-nitrosylation T Cell Cytokine Production Protein Localization To Plasma Membrane Hard Palate Development	Developmental Process Multicellular Organismal Development Anatomical Structure Development Anatomical Structure Morphogenesis System Development Positive Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Development Regulation Of Epithelial Cell Proliferation Regulation Of Cell Adhesion Generation Of Neurons Regulation Of Cell Differentiation Organ Development Nervous System Development Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Cellular Protein Metabolic Process Neurogenesis Neuron Differentiation Embryonic Skeletal System Development Signal Transduction Cell Fate Determination Positive Regulation Of Protein Metabolic Process Cell Development Cell Differentiation Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Junction Assembly Signaling Regulation Of Cellular Component Organization Pattern Specification Process Cell Communication Cardiovascular System Development Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Negative Regulation Of Dendrite Morphogenesis Regulation Of Apoptotic Process Regulation Of Postsynaptic Membrane Potential Anterior/posterior Pattern Specification Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Embryonic Heart Tube Development Central Nervous System Development Embryonic Pattern Specification Regulation Of Cell Death Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Ossification
Tagcloud ?		amphiphysin baiap2l1 bar bin cdkn2a ch5183284 constitutive debio deltabar dimerization discovered f3 fgfr fgfr3 fibroblast fusion harboring oncogenic rat rat2 rb1 rearrangements rvs screens signature suppressive transfectant transforming tumorigenic	16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 mef2c microdeletions microduplications scn2a spasms stxbp1 xq28
Tagcloud (Difference) ?		amphiphysin baiap2l1 bar bin cdkn2a ch5183284 constitutive debio deltabar dimerization discovered f3 fgfr fgfr3 fibroblast fusion harboring oncogenic rat rat2 rb1 rearrangements rvs screens signature suppressive transfectant transforming tumorigenic	16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 mef2c microdeletions microduplications scn2a spasms stxbp1 xq28
Tagcloud (Intersection) ?