DYNC1I2 and DYNLRB1

Number of citations of the paper that reports this interaction (PMID 22863883)
15

Data Source:
BioGRID (two hybrid, biochemical)

		DYNC1I2	DYNLRB1
Gene Name		dynein, cytoplasmic 1, intermediate chain 2	dynein, light chain, roadblock-type 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle	Cytoplasm Centrosome Cytoplasmic Dynein Complex Microtubule Membrane Primary Cilium Ciliary Tip
	Molecular Function	Microtubule Motor Activity	Microtubule Motor Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Microtubule-based Movement Metabolic Process Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Transport Organelle Organization Microtubule-based Movement Visual Behavior Metabolic Process
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System	Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: DCTN1 DYNLRB1 DYNLT3 PNN	6 interactors: CPEB1 DYNC1I1 DYNC1I2 HSPH1 MPHOSPH6 MPP6
Entrez ID		1781	83658
HPRD ID		04512	06203
Ensembl ID		ENSG00000077380	ENSG00000125971
Uniprot IDs		B4DPZ3 B7ZA04 Q13409	B4DFR2 Q9NP97
PDB IDs			1Z09 2B95 2E8J 2HZ5
Enriched GO Terms of Interacting Partners?			Maturation Of 5.8S RRNA Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II RRNA Processing RRNA Metabolic Process Ribosome Biogenesis Positive Regulation Of NK T Cell Activation Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Cytoplasmic Translation Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Microtubule-based Movement Regulation Of Cytoplasmic Translation Ribonucleoprotein Complex Biogenesis Regulation Of MHC Class I Biosynthetic Process Synaptonemal Complex Assembly NcRNA Metabolic Process Synaptonemal Complex Organization Chaperone Mediated Protein Folding Requiring Cofactor
Tagcloud ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?