CNGB1 and PRPH2

Number of citations of the paper that reports this interaction (PMID 11641407)
44

Data Source:
HPRD (in vitro)

		CNGB1	PRPH2
Gene Name		cyclic nucleotide gated channel beta 1	peripherin 2 (retinal degeneration, slow)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Plasma Membrane Intracellular Cyclic Nucleotide Activated Cation Channel Complex Golgi-associated Vesicle Membrane Terminal Bouton Ciliary Membrane Transmembrane Transporter Complex	Integral Component Of Membrane
	Molecular Function	Intracellular CAMP Activated Cation Channel Activity Intracellular CGMP Activated Cation Channel Activity Voltage-gated Potassium Channel Activity Protein Binding Ligand-gated Ion Channel Activity CAMP Binding CGMP Binding
	Biological Process	Retina Homeostasis Transport Cation Transport Organelle Organization Visual Perception Phototransduction, Visible Light Sensory Perception Of Smell Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Localization To Organelle Regulation Of Membrane Potential Photoreceptor Cell Maintenance Detection Of Light Stimulus Involved In Visual Perception Protein Heterotetramerization Cytosolic Calcium Ion Homeostasis Potassium Ion Transmembrane Transport	Cell Adhesion Visual Perception Response To Low Light Intensity Stimulus Retina Development In Camera-type Eye
Pathways		Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Visual phototransduction The phototransduction cascade VxPx cargo-targeting to cilium Assembly of the primary cilium Diseases associated with visual transduction
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ABCA4 PNN PRPH2	4 interactors: CNGB1 GRAP2 PRPH ROM1
Entrez ID		1258	5961
HPRD ID		07204	01553
Ensembl ID		ENSG00000070729	ENSG00000112619
Uniprot IDs		Q14028	P23942
PDB IDs
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus Phospholipid Transfer To Membrane Response To Low Light Intensity Stimulus Response To Light Stimulus Response To Radiation Response To Light Intensity Sensory Perception Photoreceptor Cell Maintenance Response To Abiotic Stimulus Neurological System Process Phospholipid Translocation Cell Adhesion Retina Homeostasis	Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Retina Development In Camera-type Eye Neurological System Process Response To Low Light Intensity Stimulus Response To Light Stimulus Camera-type Eye Development Eye Development Response To Light Intensity Response To Radiation Camera-type Eye Photoreceptor Cell Differentiation Detection Of Light Stimulus Involved In Visual Perception Protein Heterotetramerization Sensory Organ Development Retina Vasculature Development In Camera-type Eye Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Photoreceptor Cell Maintenance Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
Tagcloud ?			accelerated adenoassociated augmentation blinding carrying degenerations electroretinogram incurable inherited insults ipd ipds neuroprotective p347s photoreceptor promise prosurvival prs r26 raav rds retinal rho rosa26 scotopic stat3 tg y705f
Tagcloud (Difference) ?			accelerated adenoassociated augmentation blinding carrying degenerations electroretinogram incurable inherited insults ipd ipds neuroprotective p347s photoreceptor promise prosurvival prs r26 raav rds retinal rho rosa26 scotopic stat3 tg y705f
Tagcloud (Intersection) ?