HAUS2

Description		HAUS augmin like complex subunit 2
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GO Annotations	Cellular Component	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding
	Biological Process	Microtubule Nucleation Centrosome Cycle Regulation Of Microtubule Nucleation Microtubule Organizing Center Organization Spindle Assembly Cell Division
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		3 interacting genes: FXYD6 MAPK6 XRCC4
Entrez ID		55142
HPRD ID		07675
Ensembl ID		ENSG00000137814
Uniprot IDs		H3BP16 Q9NVX0
PDB IDs		7SQK
Enriched GO Terms of Interacting Partners?		Septin Cytoskeleton FHA Domain Binding Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Phospholipid Translocation DNA-dependent Protein Kinase-DNA Ligase 4 Complex Positive Regulation Of Ligase Activity Immunoglobulin V(D)J Recombination DNA Ligase IV Complex Nonhomologous End Joining Complex Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity MAP Kinase Activity Response To Lithium Ion Regulation Of Plasma Membrane Organization Cellular Response To Lithium Ion Positive Regulation Of Phospholipid Transport Positive Regulation Of Sodium Ion Transmembrane Transport V(D)J Recombination Response To X-ray Protein Localization To Site Of Double-strand Break Positive Regulation Of Dendritic Spine Development Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Positive Regulation Of Transport Regulation Of Sodium Ion Transmembrane Transport Sodium Channel Regulator Activity Positive Regulation Of Sodium Ion Transport Somatic Cell DNA Recombination Somatic Diversification Of Immunoglobulins Regulation Of Membrane Lipid Distribution Regulation Of Dendritic Spine Development Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Sodium Ion Transport
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