Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ATP7A and PDZD11
Number of citations of the paper that reports this interaction (PMID
16051599
)
10
Data Source:
HPRD
(in vivo, two hybrid)
ATP7A
PDZD11
Gene Name
ATPase, Cu++ transporting, alpha polypeptide
PDZ domain containing 11
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Late Endosome
Endoplasmic Reticulum
Golgi Apparatus
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Trans-Golgi Network Transport Vesicle
Secretory Granule
Brush Border Membrane
Neuron Projection
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Region
Cytosol
Cell-cell Junction
Basolateral Plasma Membrane
Synapse
Molecular Function
Copper-exporting ATPase Activity
Copper Ion Transmembrane Transporter Activity
Copper Ion Binding
Protein Binding
ATP Binding
Superoxide Dismutase Copper Chaperone Activity
Copper-dependent Protein Binding
Protein Binding
Protein C-terminus Binding
Biological Process
Response To Reactive Oxygen Species
Blood Vessel Development
In Utero Embryonic Development
Release Of Cytochrome C From Mitochondria
Blood Vessel Remodeling
Regulation Of Oxidative Phosphorylation
Tryptophan Metabolic Process
Tyrosine Metabolic Process
Catecholamine Metabolic Process
Copper Ion Transport
Cellular Copper Ion Homeostasis
Mitochondrion Organization
Lactation
Locomotory Behavior
Response To Iron(III) Ion
Response To Zinc Ion
Detoxification Of Copper Ion
Regulation Of Gene Expression
Copper Ion Import
Plasma Membrane Copper Ion Transport
Peptidyl-lysine Modification
Removal Of Superoxide Radicals
Cerebellar Purkinje Cell Differentiation
Pyramidal Neuron Development
Central Nervous System Neuron Development
Extracellular Matrix Organization
Collagen Fibril Organization
Hair Follicle Morphogenesis
Ion Transmembrane Transport
T-helper Cell Differentiation
Epinephrine Metabolic Process
Norepinephrine Metabolic Process
Dopamine Metabolic Process
Norepinephrine Biosynthetic Process
Serotonin Metabolic Process
Positive Regulation Of Catalytic Activity
Pigmentation
Negative Regulation Of Neuron Apoptotic Process
Skin Development
ATP Metabolic Process
Elastic Fiber Assembly
Lung Alveolus Development
Negative Regulation Of Metalloenzyme Activity
Positive Regulation Of Metalloenzyme Activity
Neuron Projection Morphogenesis
Dendrite Morphogenesis
Cartilage Development
Positive Regulation Of Oxidoreductase Activity
Elastin Biosynthetic Process
Transmembrane Transport
Copper Ion Export
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Biotin Metabolic Process
Exocytosis
Neurotransmitter Secretion
Asymmetric Protein Localization
Pantothenate Metabolic Process
Ion Transmembrane Transport
Small Molecule Metabolic Process
Maintenance Of Epithelial Cell Apical/basal Polarity
Transmembrane Transport
Protein Localization To Basolateral Plasma Membrane
Pathways
Ion transport by P-type ATPases
Ion channel transport
Detoxification of Reactive Oxygen Species
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
SLC-mediated transmembrane transport
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Ion transport by P-type ATPases
Defective AMN causes hereditary megaloblastic anemia 1
Ion channel transport
Transport of vitamins, nucleosides, and related molecules
Defects in cobalamin (B12) metabolism
Defective GIF causes intrinsic factor deficiency
Vitamin B5 (pantothenate) metabolism
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Biotin transport and metabolism
Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
ATOX1
CP
PDZD11
4 interactors:
ATP2B2
ATP7A
PLEKHA5
SIGMAR1
Entrez ID
538
51248
HPRD ID
02054
06622
Ensembl ID
ENSG00000165240
ENSG00000120509
Uniprot IDs
B4DRW0
Q04656
Q762B6
Q5EBL8
PDB IDs
1AW0
1KVI
1KVJ
1Q8L
1S6O
1S6U
1Y3J
1Y3K
1YJR
1YJT
1YJU
1YJV
2AW0
2G9O
2GA7
2K1R
2KIJ
2KMV
2KMX
3CJK
Enriched GO Terms of Interacting Partners
?
Copper Ion Transport
Transition Metal Ion Homeostasis
Intracellular Copper Ion Transport
Transmembrane Transport
Ion Transport
Protein Localization To Basolateral Plasma Membrane
Maintenance Of Epithelial Cell Apical/basal Polarity
Maintenance Of Apical/basal Cell Polarity
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
Copper Ion Transmembrane Transport
Maintenance Of Cell Polarity
Pantothenate Metabolic Process
Biotin Metabolic Process
Cellular Chemical Homeostasis
Ion Homeostasis
Cellular Copper Ion Homeostasis
Cellular Homeostasis
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Copper Ion Homeostasis
Asymmetric Protein Localization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Metal Ion Transport
Chemical Homeostasis
Cation Transport
Ion Transmembrane Transport
Transport
Homeostatic Process
Cellular Iron Ion Homeostasis
Water-soluble Vitamin Metabolic Process
Neurotransmitter Secretion
Vitamin Metabolic Process
Iron Ion Homeostasis
Regulation Of Neurotransmitter Levels
Protein Localization To Plasma Membrane
Establishment Of Localization In Cell
Neurotransmitter Transport
Establishment Or Maintenance Of Cell Polarity
Response To Reactive Oxygen Species
Plasma Membrane Organization
Cellular Localization
Cerebellar Purkinje Cell Differentiation
Serotonin Metabolic Process
Cerebellar Purkinje Cell Layer Morphogenesis
Cerebellar Cortex Formation
Cell Differentiation In Hindbrain
Cerebellar Purkinje Cell Layer Development
Cerebellar Cortex Morphogenesis
Cerebellum Morphogenesis
Hindbrain Morphogenesis
Lactation
Cerebellar Cortex Development
Regulation Of Oxidoreductase Activity
Phenol-containing Compound Metabolic Process
Body Fluid Secretion
Cerebellum Development
Elastin Biosynthetic Process
Negative Regulation Of Citrulline Biosynthetic Process
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Negative Regulation Of Arginine Catabolic Process
Calcium Ion Import Across Plasma Membrane
Plasma Membrane Copper Ion Transport
Otolith Mineralization
Negative Regulation Of The Force Of Heart Contraction
Metencephalon Development
Mammary Gland Development
Hindbrain Development
Calcium Ion Import Into Cell
Copper Ion Export
Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process
Negative Regulation Of Cardiac Muscle Adaptation
Elastin Metabolic Process
Detoxification Of Copper Ion
Negative Regulation Of Adrenergic Receptor Signaling Pathway
Central Nervous System Neuron Differentiation
Locomotory Behavior
Regulation Of Neuron Apoptotic Process
Response To Iron(III) Ion
Epinephrine Metabolic Process
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Epidermis Development
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Positive Regulation Of CAMP-dependent Protein Kinase Activity
Regulation Of Neuron Death
Norepinephrine Biosynthetic Process
Negative Regulation Of Metalloenzyme Activity
Regulation Of Adrenergic Receptor Signaling Pathway
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Ribonucleotide Metabolic Process
System Development
Purine Nucleotide Metabolic Process
Tagcloud
?
96h
basolateral
cd1
copper
cuproenzyme
deliver
deprivation
duodenum
enterocytes
grew
iec
influences
irrespective
kd
ki67
menkes
pcna
perturbed
proliferating
pumping
relate
rodent
shrna
silenced
slower
transporting
trigger
unaltered
unexpected
Tagcloud (Difference)
?
96h
basolateral
cd1
copper
cuproenzyme
deliver
deprivation
duodenum
enterocytes
grew
iec
influences
irrespective
kd
ki67
menkes
pcna
perturbed
proliferating
pumping
relate
rodent
shrna
silenced
slower
transporting
trigger
unaltered
unexpected
Tagcloud (Intersection)
?