NECAP2 and NMI

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NECAP2	NMI
Gene Name		NECAP endocytosis associated 2	N-myc (and STAT) interactor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Plasma Membrane Coated Pit Clathrin Vesicle Coat	Nucleoplasm Cytoplasm
	Molecular Function		Transcription Cofactor Activity Protein Binding
	Biological Process	Endocytosis Protein Transport	Transcription From RNA Polymerase II Promoter Inflammatory Response JAK-STAT Cascade Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AP2B1 APP NMI PLSCR1 TRAF2	44 interactors: BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CNKSR3 COPS7B CYP2E1 EMILIN1 GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MTMR6 MTMR9 MYC MYCN NECAP2 POMZP3 PSMA1 SCEL SFR1 SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 TRAF5 TRIP12 TUBA3C TUBA3E TXLNA TXLNB
Entrez ID		55707	9111
HPRD ID		07674	04632
Ensembl ID		ENSG00000157191	ENSG00000123609
Uniprot IDs		Q9NVZ3	Q13287 Q8WTW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Defense Response Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Immune System Process Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Synaptic Growth At Neuromuscular Junction Positive Regulation Of Innate Immune Response Collateral Sprouting In Absence Of Injury Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Apoptotic Process Platelet Activation Programmed Cell Death Positive Regulation Of Hydrolase Activity Cell Death Death Regulation Of Signal Transduction Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Innate Immune Response Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Phosphatidylserine Biosynthetic Process Regulation Of Signaling Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Immune System Process Positive Regulation Of Proteolysis Neuron Remodeling Response To Stress Positive Regulation Of Protein Homodimerization Activity Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phospholipid Scrambling Cellular Response To Nitric Oxide Positive Regulation Of Catalytic Activity Regulation Of Endopeptidase Activity Axon Guidance Regulation Of Immunoglobulin Secretion Response To Nitric Oxide Regulation Of Peptidase Activity Response To Oxidative Stress Blood Coagulation Inflammatory Response Hemostasis Regulation Of Cell Activation Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Cellular Copper Ion Homeostasis Response To External Stimulus Regulation Of Protein Homodimerization Activity	JAK-STAT Cascade JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Positive Regulation Of Stem Cell Proliferation Regulation Of Cell Proliferation Response To Growth Hormone Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Regulation Of Stem Cell Proliferation Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Development Of Secondary Male Sexual Characteristics Cellular Response To Cytokine Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cytokine-mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Histone H3-K4 Methylation Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Response To Cytokine Regulation Of Apoptotic Process Creatinine Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Allantoin Metabolic Process Isoleucine Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Gene Expression Heterocycle Metabolic Process Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway RNA Metabolic Process Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics
Tagcloud ?		actin anxa2 automated beyond cofilin coincided dephosphorylation depletion dnajc6 egfr endocytosis endosomes fgd6 gdi2 hax1 hbl100 inactive knockdown mb mda mediator mediators re rnas s3a s3e semi severing tnbc	augment augments bait cbp coactivator coil coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Difference) ?		actin anxa2 automated beyond cofilin coincided dephosphorylation depletion dnajc6 egfr endocytosis endosomes fgd6 gdi2 hax1 hbl100 inactive knockdown mb mda mediator mediators re rnas s3a s3e semi severing tnbc	augment augments bait cbp coactivator coil coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Intersection) ?