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PKP1 and KRT14
Number of citations of the paper that reports this interaction (PubMedID
10852826
)
0
Data Source:
HPRD
(in vitro)
PKP1
KRT14
Description
plakophilin 1
keratin 14
Image
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Nucleoplasm
Cytoplasm
Intermediate Filament
Plasma Membrane
Adherens Junction
Cytoplasmic Stress Granule
Membrane
Desmosome
Perinuclear Region Of Cytoplasm
Anchoring Junction
Nuclear Stress Granule
Ficolin-1-rich Granule Membrane
Cornified Envelope
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Keratin Filament
Basal Part Of Cell
Extracellular Exosome
Cell Periphery
Molecular Function
DNA Binding
RNA Binding
Protein Binding
Lamin Binding
Intermediate Filament Binding
Structural Constituent Of Skin Epidermis
Cadherin Binding
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
Keratin Filament Binding
Biological Process
Desmosome Assembly
Desmosome Maintenance
Cell Adhesion
Signal Transduction
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-cell Adhesion
Transepithelial Water Transport
Ameloblast Differentiation
Intermediate Filament Bundle Assembly
Positive Regulation Of Keratinocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cell-cell Adhesion
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Cap-dependent Translational Initiation
Positive Regulation Of Protein Localization To Membrane
Morphogenesis Of An Epithelium
Epidermis Development
Response To Radiation
Keratinocyte Differentiation
Hair Cycle
Intermediate Filament Organization
Intermediate Filament Bundle Assembly
Stem Cell Differentiation
Pathways
Apoptotic cleavage of cell adhesion proteins
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Type I hemidesmosome assembly
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Developmental Lineage of Mammary Gland Myoepithelial Cells
Drugs
Zinc
Zinc acetate
Diseases
Ectodermal dysplasia/skin fragility syndrome
Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Dermatopathia pigmentosa reticularis
Naegeli-Franceschetti-Jadassohn syndrome
GWAS
Panic disorder (
19165232
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
17 interacting genes:
ARMC8
BICDL2
CARD10
CEP76
DSC1
DSG1
DSP
GOLGA2
GTF2IRD1
HOOK2
HSF2BP
KRT14
KRT8
NFKBID
TNS2
UCHL5
VIM
35 interacting genes:
ABI2
ABI3
AMOT
APC
BFSP2
CTTNBP2
DRC4
DST
ENKD1
HGS
HSPA5
KIFC3
KRT1
KRT3
KRT4
KRT5
KRT6C
KRT72
KRT77
KRT78
KRT79
KRT80
KRT81
KRT85
KRT86
OIP5
PKP1
PRPH
PUS10
SDCBP
SMARCE1
TCHP
TRADD
UBASH3A
USHBP1
Entrez ID
5317
3861
HPRD ID
03579
01017
Ensembl ID
ENSG00000081277
ENSG00000186847
Uniprot IDs
Q13835
P02533
PDB IDs
1XM9
3TNU
6JFV
Enriched GO Terms of Interacting Partners
?
Cornified Envelope
Desmosome
Intermediate Filament
Keratin Filament Binding
Ficolin-1-rich Granule Membrane
Intermediate Filament Organization
Scaffold Protein Binding
Desmosome Organization
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Cytoskeleton
Epidermis Development
Anchoring Junction
Cell-cell Junction Organization
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament
Keratin Filament
Keratinization
Cytoskeleton Organization
Supramolecular Fiber Organization
Organelle Organization
Anchoring Junction
Cytosol
Cytoskeleton
Extracellular Exosome
Desmosome
Cell-cell Junction Organization
Cell Junction Organization
Adherens Junction
Polymeric Cytoskeletal Fiber
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Cell-cell Junction Assembly
Actin-based Cell Projection
Intermediate Filament Cytoskeleton
Microtubule Binding
Microtubule Cytoskeleton
Cell Junction Assembly
Cornified Envelope
Protein Binding
SCAR Complex
Positive Regulation Of Exosomal Secretion
Regulation Of Modification Of Postsynaptic Structure
Structural Molecule Activity
Signaling Adaptor Activity
Lamellipodium
Microtubule
Regulation Of Exosomal Secretion
Regulation Of Modification Of Synaptic Structure
Microtubule Plus-end Binding
Cell-cell Junction Maintenance
Cytoskeletal Anchor Activity
Structural Constituent Of Cytoskeleton
Regulation Of Cell Projection Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Intermediate Filament Polymerization
Interleukin-5 Receptor Complex
COP9 Signalosome
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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