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KRT14 and KRT5
Number of citations of the paper that reports this interaction (PubMedID
8636216
)
68
Data Source:
HPRD
(in vitro)
KRT14
KRT5
Description
keratin 14
keratin 5
Image
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Keratin Filament
Basal Part Of Cell
Extracellular Exosome
Cell Periphery
Nucleus
Cytoplasm
Cytosol
Intermediate Filament
Membrane
Keratin Filament
Extracellular Exosome
Molecular Function
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
Keratin Filament Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
Scaffold Protein Binding
Biological Process
Morphogenesis Of An Epithelium
Epidermis Development
Response To Radiation
Keratinocyte Differentiation
Hair Cycle
Intermediate Filament Organization
Intermediate Filament Bundle Assembly
Stem Cell Differentiation
Epidermis Development
Response To Mechanical Stimulus
Regulation Of Cell Migration
Keratinization
Regulation Of Protein Localization
Intermediate Filament Polymerization
Intermediate Filament Organization
Pathways
Type I hemidesmosome assembly
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Developmental Lineage of Mammary Gland Myoepithelial Cells
Type I hemidesmosome assembly
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Myoepithelial Cells
Developmental Lineage of Mammary Stem Cells
Drugs
Zinc
Zinc acetate
Zinc
Zinc acetate
Diseases
Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Dermatopathia pigmentosa reticularis
Naegeli-Franceschetti-Jadassohn syndrome
Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Dowling-Degos disease
GWAS
Basal cell carcinoma (
24403052
25855136
27539887
31174203
33549134
)
Cutaneous squamous cell carcinoma (
32041948
)
Keratinocyte cancer (MTAG) (
31174203
)
Non-melanoma skin cancer (
29739929
)
Squamous cell carcinoma (
31174203
)
Interacting Genes
35 interacting genes:
ABI2
ABI3
AMOT
APC
BFSP2
CTTNBP2
DRC4
DST
ENKD1
HGS
HSPA5
KIFC3
KRT1
KRT3
KRT4
KRT5
KRT6C
KRT72
KRT77
KRT78
KRT79
KRT80
KRT81
KRT85
KRT86
OIP5
PKP1
PRPH
PUS10
SDCBP
SMARCE1
TCHP
TRADD
UBASH3A
USHBP1
30 interacting genes:
ALOX12
ALOX12B
APC
DSP
DST
EVPL
INCA1
KIFC3
KRT1
KRT13
KRT14
KRT15
KRT18
KRT24
KRT25
KRT27
KRT28
KRT31
KRT32
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT40
PKP2
RNF26
TCHP
UBE3A
Entrez ID
3861
3852
HPRD ID
01017
01010
Ensembl ID
ENSG00000186847
ENSG00000186081
Uniprot IDs
P02533
P13647
PDB IDs
3TNU
6JFV
3TNU
6JFV
Enriched GO Terms of Interacting Partners
?
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament
Keratin Filament
Keratinization
Cytoskeleton Organization
Supramolecular Fiber Organization
Organelle Organization
Anchoring Junction
Cytosol
Cytoskeleton
Extracellular Exosome
Desmosome
Cell-cell Junction Organization
Cell Junction Organization
Adherens Junction
Polymeric Cytoskeletal Fiber
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Cell-cell Junction Assembly
Actin-based Cell Projection
Intermediate Filament Cytoskeleton
Microtubule Binding
Microtubule Cytoskeleton
Cell Junction Assembly
Cornified Envelope
Protein Binding
SCAR Complex
Positive Regulation Of Exosomal Secretion
Regulation Of Modification Of Postsynaptic Structure
Structural Molecule Activity
Signaling Adaptor Activity
Lamellipodium
Microtubule
Regulation Of Exosomal Secretion
Regulation Of Modification Of Synaptic Structure
Microtubule Plus-end Binding
Cell-cell Junction Maintenance
Cytoskeletal Anchor Activity
Structural Constituent Of Cytoskeleton
Regulation Of Cell Projection Assembly
Regulation Of Protein Folding In Endoplasmic Reticulum
Intermediate Filament Polymerization
Interleukin-5 Receptor Complex
COP9 Signalosome
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament Organization
Intermediate Filament
Structural Constituent Of Skin Epidermis
Keratin Filament
Structural Molecule Activity
Supramolecular Fiber Organization
Cytoskeleton Organization
Tissue Morphogenesis
Epithelial Cell Differentiation
Morphogenesis Of An Epithelium
Cytoskeleton
Organelle Organization
Extracellular Exosome
Cytosol
Anatomical Structure Morphogenesis
Epidermis Development
Intermediate Filament Cytoskeleton
Developmental Process
Keratinization
Cellular Developmental Process
Cell Differentiation
Structural Constituent Of Cytoskeleton
Cornified Envelope
Tissue Development
Desmosome
Hair Cycle
Peptide Cross-linking
Arachidonate 12(S)-lipoxygenase Activity
Wound Healing
Anchoring Junction
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Hair Follicle Morphogenesis
Adherens Junction
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Establishment Of Skin Barrier
Hepoxilin Biosynthetic Process
Polymeric Cytoskeletal Fiber
Cardiac Muscle Cell-cardiac Muscle Cell Adhesion
Skin Epidermis Development
Intermediate Filament Bundle Assembly
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Lipoxygenase Pathway
Negative Regulation Of Cyclin-dependent Protein Kinase Activity
Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Keratinocyte Differentiation
Desmosome Organization
Scaffold Protein Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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