NEO1

Description		neogenin 1
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GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Plasma Membrane Cell Surface Membrane Growth Cone Intracellular Vesicle Plasma Membrane Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Signaling Receptor Activity Co-receptor Binding Cadherin Binding BMP Receptor Binding
	Biological Process	Neuron Migration Regulation Of DNA-templated Transcription Intracellular Iron Ion Homeostasis Cell Adhesion Axon Guidance Myoblast Fusion Protein Secretion Positive Regulation Of BMP Signaling Pathway Regulation Of Axon Regeneration Negative Regulation Of Axon Regeneration Negative Regulation Of Protein Secretion Multicellular Organismal-level Iron Ion Homeostasis Cell-cell Adhesion Trans-synaptic Signaling, Modulating Synaptic Transmission
Pathways		Netrin-1 signaling Myogenesis
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dentures ( 31235808) Face memory ( 31596458) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Red cell distribution width ( 32888494) Resting heart rate ( 27798624) Urate levels ( 31578528)
Interacting Genes		6 interacting genes: MTDH NTN1 NTN3 PITPNA PTK2 TTN
Entrez ID		4756
HPRD ID		03549
Ensembl ID		ENSG00000067141
Uniprot IDs		Q59FP8 Q92859
PDB IDs		1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L
Enriched GO Terms of Interacting Partners?		Detection Of Muscle Stretch Axon Guidance Axonogenesis Neuron Projection Guidance Anatomical Structure Morphogenesis Response To Muscle Stretch Neuron Projection Morphogenesis Cell Projection Morphogenesis Detection Of Mechanical Stimulus Cell Projection Organization Neuron Projection Development Detection Of Abiotic Stimulus Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Protein Tyrosine Kinase Activity Quaternary Ammonium Group Binding Skeletal Muscle Myosin Thick Filament Assembly Cdc42 Protein Signal Transduction Phosphatidylglycerol Binding Myosin Filament Assembly Plasma Membrane Bounded Cell Projection Organization Phosphatidylcholine Transporter Activity Phosphatidylcholine Transfer Activity Response To Mechanical Stimulus Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Positive Regulation Of Macrophage Proliferation Telethonin Binding Skeletal Muscle Thin Filament Assembly Chemorepulsion Of Axon Anterior/posterior Axon Guidance Intercellular Canaliculus Signal Complex Assembly Mammary Gland Duct Morphogenesis Netrin-activated Signaling Pathway Detection Of Stimulus Striated Muscle Thin Filament Regulation Of Cell Junction Assembly Substrate-dependent Cell Migration, Cell Extension Phosphatidylinositol Transfer Activity JUN Kinase Binding Actin Cytoskeleton Protein Kinase A Signaling Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Motor Neuron Migration Cytoplasm Vascular Endothelial Cell Response To Fluid Shear Stress Muscle Alpha-actinin Binding
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