PIP4K2A and GSTK1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PIP4K2A	GSTK1
Gene Name		phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	glutathione S-transferase kappa 1
Image
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus Cytosol Plasma Membrane	Intracellular Mitochondrial Inner Membrane Mitochondrial Matrix Peroxisome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity	Glutathione Transferase Activity Glutathione Peroxidase Activity Receptor Binding Protein Disulfide Oxidoreductase Activity
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Megakaryocyte Development Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation	Glutathione Metabolic Process Epithelial Cell Differentiation Oxidation-reduction Process
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs			Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: BTK GSTK1 RAC1 TEC	6 interactors: CCNDBP1 FAM9B GRB2 PEX5 PIP4K2A PRPF19
Entrez ID		5305	373156
HPRD ID		11931	13613
Ensembl ID		ENSG00000150867	ENSG00000197448
Uniprot IDs		P48426	E9PFN5 Q6FII1 Q9Y2Q3
PDB IDs		2YBX	1YZX 3RPN 3RPP
Enriched GO Terms of Interacting Partners?		Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Tissue Development Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Inner Ear Morphogenesis Innate Immune Response Ear Morphogenesis Regulation Of B Cell Cytokine Production Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Mesoderm Development Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Cellular Response To Molecule Of Fungal Origin Inner Ear Development Response To Reactive Oxygen Species Pallium Development Cell Differentiation Protein Autophosphorylation Engulfment Of Apoptotic Cell Ear Development Response To Molecule Of Fungal Origin Vestibular Reflex Mast Cell Chemotaxis Immune Response Regulation Of Immune System Process Defense Response Adaptive Immune Response Peptidyl-tyrosine Phosphorylation Telencephalon Development Regulation Of Apoptotic Process Positive Regulation Of Cell Activation Regulation Of Cell Death Embryonic Organ Morphogenesis Tangential Migration From The Subventricular Zone To The Olfactory Bulb Apoptotic Signaling Pathway Olfactory Bulb Interneuron Development Axon Guidance Regulation Of Lymphocyte Activation Regulation Of Hydrogen Peroxide Metabolic Process Cell Development	Signal Transduction In Response To DNA Damage Generation Of Catalytic Spliceosome For First Transesterification Step Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Lipid Modification Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Lipid Metabolic Process Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Regulation Of Protein Complex Assembly Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Protein Oligomerization Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Generation Of Neurons Protein Import Into Peroxisome Matrix Spliceosomal Tri-snRNP Complex Assembly Neurogenesis Megakaryocyte Development Protein Oligomerization Cell Development System Development In Utero Embryonic Development Cellular Component Assembly Inner Cell Mass Cell Proliferation Double-strand Break Repair Via Nonhomologous End Joining Megakaryocyte Differentiation Labyrinthine Layer Morphogenesis Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Lipid Biosynthetic Process Very Long-chain Fatty Acid Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Embryonic Placenta Morphogenesis Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Blastocyst Growth Regulation Of Astrocyte Differentiation Multicellular Organismal Development Protein K63-linked Ubiquitination Positive Regulation Of RNA Splicing Anatomical Structure Development Nervous System Development
Tagcloud ?		accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts
Tagcloud (Difference) ?		accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts
Tagcloud (Intersection) ?