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PIP4K2A
Gene Name
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Image
Gene Ontology Annotations
Cellular Component
Cellular_component
Nucleus
Cytosol
Plasma Membrane
Molecular Function
ATP Binding
1-phosphatidylinositol-4-phosphate 5-kinase Activity
1-phosphatidylinositol-5-phosphate 4-kinase Activity
Biological Process
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Megakaryocyte Development
Small Molecule Metabolic Process
Phosphatidylinositol Phosphorylation
Pathways
Synthesis of PIPs at the plasma membrane
Metabolism of lipids and lipoproteins
Phospholipid metabolism
PI Metabolism
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-protein Interactions
4 interactors:
BTK
GSTK1
RAC1
TEC
Entrez ID
5305
HPRD ID
11931
Ensembl ID
ENSG00000150867
Uniprot IDs
P48426
PDB IDs
2YBX
Enriched GO Terms of Interacting Partners
?
Fc-epsilon Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Peptidyl-tyrosine Autophosphorylation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Tissue Development
Immune Response-regulating Signaling Pathway
Regulation Of Cell Activation
Positive Regulation Of Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Inner Ear Morphogenesis
Innate Immune Response
Ear Morphogenesis
Regulation Of B Cell Cytokine Production
Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Mesoderm Development
Embryonic Olfactory Bulb Interneuron Precursor Migration
Negative Regulation Of Interleukin-23 Production
Cellular Response To Molecule Of Fungal Origin
Inner Ear Development
Response To Reactive Oxygen Species
Pallium Development
Cell Differentiation
Protein Autophosphorylation
Engulfment Of Apoptotic Cell
Ear Development
Response To Molecule Of Fungal Origin
Vestibular Reflex
Mast Cell Chemotaxis
Immune Response
Regulation Of Immune System Process
Defense Response
Adaptive Immune Response
Peptidyl-tyrosine Phosphorylation
Telencephalon Development
Regulation Of Apoptotic Process
Positive Regulation Of Cell Activation
Regulation Of Cell Death
Embryonic Organ Morphogenesis
Tangential Migration From The Subventricular Zone To The Olfactory Bulb
Apoptotic Signaling Pathway
Olfactory Bulb Interneuron Development
Axon Guidance
Regulation Of Lymphocyte Activation
Regulation Of Hydrogen Peroxide Metabolic Process
Cell Development
Tagcloud
?
accompanied
amplification
bearing
cancers
dramatic
encoding
express
homozygous
importantly
kinases
knocking
lethality
littermates
phosphate
phosphatidylinositol
plastic
preventing
ros
senescence
subset
synthetic
tp53
treating
viable
xenografts