PHYH and ACSL6

Number of citations of the paper that reports this interaction (PubMedID 12767919)
0

Data Source:
HPRD (in vitro)

		PHYH	ACSL6
Description		phytanoyl-CoA 2-hydroxylase	acyl-CoA synthetase long chain family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol 9+0 Non-motile Cilium	Mitochondrion Mitochondrial Outer Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Catalytic Activity Protein Binding Ferrous Iron Binding Oxidoreductase Activity Carboxylic Acid Binding L-ascorbic Acid Binding Metal Ion Binding Phytanoyl-CoA Dioxygenase Activity Dioxygenase Activity	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Enzyme Binding Protein Homodimerization Activity Arachidonate-CoA Ligase Activity
	Biological Process	Fatty Acid Alpha-oxidation 2-oxoglutarate Metabolic Process Fatty Acid Metabolic Process Isoprenoid Metabolic Process 2-oxobutyrate Catabolic Process Methyl-branched Fatty Acid Metabolic Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Neuroblast Proliferation Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		Alpha-oxidation of phytanate Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Synthesis of very long-chain fatty acyl-CoAs
Drugs		Antihemophilic factor, human recombinant Ascorbic acid Lonoctocog alfa Moroctocog alfa
Diseases		Refsum disease; Heredopathia atactica polyneuritiformis
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 22412388 28067908) Inflammatory bowel disease ( 23128233 28067908) Perceived unattractiveness to mosquitoes ( 28199695) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PATJ PEX7 PHYHIP SIRPA TOM1L1	3 interacting genes: PCMTD2 PHYH ZNF655
Entrez ID		5264	23305
HPRD ID		03609	09190
Ensembl ID		ENSG00000107537	ENSG00000164398
Uniprot IDs		O14832	A0A494BZW8 A0A494C0B6 A0A494C0J9 A0A499FJL5 B2RB13 B4DFW3 C9J8C7 Q9UKU0
PDB IDs		2A1X
Enriched GO Terms of Interacting Partners?			Glycine Amidinotransferase Activity Amidinotransferase Activity Homogentisate 1,2-dioxygenase Activity 2-oxobutyrate Catabolic Process Phytanoyl-CoA Dioxygenase Activity
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