ACSL6 and PHYH

Number of citations of the paper that reports this interaction (PMID 12767919)
3

Data Source:
HPRD (in vitro)

		ACSL6	PHYH
Gene Name		acyl-CoA synthetase long-chain family member 6	phytanoyl-CoA 2-hydroxylase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Mitochondrion Peroxisome Peroxisomal Matrix
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Enzyme Binding Protein Homodimerization Activity	Protein Binding Electron Carrier Activity L-ascorbic Acid Binding Metal Ion Binding Cofactor Binding Phytanoyl-CoA Dioxygenase Activity
	Biological Process	Response To Hypoxia Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Neuroblast Proliferation Response To Nutrient Phospholipid Biosynthetic Process Response To Gravity Positive Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Neuron Projection Development Fatty Acid Transport Triglyceride Biosynthetic Process Cellular Response To Insulin Stimulus Long-chain Fatty-acyl-CoA Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Response To Steroid Hormone Neuron Development	Fatty Acid Alpha-oxidation Isoprenoid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Methyl-branched Fatty Acid Metabolic Process
Pathways		Fatty Acyl-CoA Biosynthesis Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis Synthesis of very long-chain fatty acyl-CoAs	Alpha-oxidation of phytanate Metabolism of lipids and lipoproteins Peroxisomal lipid metabolism
Drugs
Diseases
GWAS		Crohn's disease ( 22412388) Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		1 interactors: PHYH	9 interactors: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PEX7 PHYHIP TOM1L1
Entrez ID		23305	5264
HPRD ID		09190	03609
Ensembl ID		ENSG00000164398	ENSG00000107537
Uniprot IDs		B2RB13 B4DFW3 Q9UKU0	O14832
PDB IDs			2A1X
Enriched GO Terms of Interacting Partners?		Methyl-branched Fatty Acid Metabolic Process Fatty Acid Alpha-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Isoprenoid Metabolic Process Cellular Lipid Catabolic Process Lipid Modification Carboxylic Acid Catabolic Process Lipid Catabolic Process Fatty Acid Metabolic Process Monocarboxylic Acid Metabolic Process	Transport Platelet Degranulation Regulation Of Neuron Differentiation Steroid Hormone Receptor Complex Assembly Positive Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Generation Of Neurons Neurogenesis Regulation Of Neurogenesis Synaptic Growth At Neuromuscular Junction Establishment Of Localization In Cell Collateral Sprouting In Absence Of Injury Regulation Of Cell Development Negative Regulation Of Neuron Differentiation Platelet Activation Intracellular Receptor Signaling Pathway Nervous System Development Collateral Sprouting Axon Midline Choice Point Recognition Cellular Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Ether Lipid Biosynthetic Process Axon Choice Point Recognition Response To Abiotic Stimulus Negative Regulation Of Neurogenesis Neuron Remodeling Ether Lipid Metabolic Process Fatty Acid Metabolic Process Lipid Metabolic Process Negative Regulation Of Cell Development Exocytosis Positive Regulation Of Triglyceride Biosynthetic Process Response To Gravity Protein Import Into Peroxisome Matrix Negative Regulation Of Microtubule Polymerization Regulation Of Neuron Projection Development Long-chain Fatty-acyl-CoA Biosynthetic Process Blood Coagulation, Intrinsic Pathway Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Protein Autophosphorylation Regulation Of Mitotic Cell Cycle Intracellular Transport Blood Coagulation Protein Complex Localization Fatty-acyl-CoA Biosynthetic Process Cellular Copper Ion Homeostasis Hemostasis Regulation Of Cell Differentiation Cell Differentiation Response To Stress Positive Regulation Of Fatty Acid Transport
Tagcloud ?			168phya asymmetric bacillus belonged bpp bpps crystallized di dii explaining glycol grew hcl histidine hjb17 incomplete p1211 phyht phyp phytases phytate polyethylene precipitant propeller refolding synchrotron trihydrate tris vapour
Tagcloud (Difference) ?			168phya asymmetric bacillus belonged bpp bpps crystallized di dii explaining glycol grew hcl histidine hjb17 incomplete p1211 phyht phyp phytases phytate polyethylene precipitant propeller refolding synchrotron trihydrate tris vapour
Tagcloud (Intersection) ?