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PHYH

Name phytanoyl-CoA 2-hydroxylase
Structure PDB 2A1X
Interactors 11 interactors: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PATJ PEX7 PHYHIP SIRPA TOM1L1
GO Annotations Cellular Component
  • Peroxisome
  • Peroxisomal Matrix
  • Cytosol
  • 9+0 Non-motile Cilium
Molecular Function
  • Catalytic Activity
  • Protein Binding
  • Ferrous Iron Binding
  • Oxidoreductase Activity
  • Carboxylic Acid Binding
  • L-ascorbic Acid Binding
  • Metal Ion Binding
  • Phytanoyl-CoA Dioxygenase Activity
  • Dioxygenase Activity
Biological Process
  • Fatty Acid Alpha-oxidation
  • 2-oxoglutarate Metabolic Process
  • Fatty Acid Metabolic Process
  • Isoprenoid Metabolic Process
  • 2-oxobutyrate Catabolic Process
  • Methyl-branched Fatty Acid Metabolic Process
Pathways
  • Alpha-oxidation of phytanate
  • Peroxisomal protein import
  • Peroxisomal protein import
  • TYSND1 cleaves peroxisomal proteins
Drugs
  • Antihemophilic factor, human recombinant
  • Ascorbic acid
  • Lonoctocog alfa
  • Moroctocog alfa
Diseases
  • Refsum disease; Heredopathia atactica polyneuritiformis
GWAS No GWAS studies recorded
Entrez ID 5264
HPRD ID 03609
Ensembl ID ENSG00000107537
Uniprot IDs O14832
PDB IDs 2A1X

© Madhavi K. Ganapathiraju 2012-2026