ABCB1 and BCCIP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ABCB1	BCCIP
Gene Name		ATP-binding cassette, sub-family B (MDR/TAP), member 1	BRCA2 and CDKN1A interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex
	Molecular Function	Transporter Activity Protein Binding ATP Binding Xenobiotic-transporting ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances	Protein Binding Kinase Regulator Activity Poly(A) RNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transport Drug Transmembrane Transport Response To Drug Xenobiotic Transport Small Molecule Metabolic Process Transmembrane Transport Stem Cell Proliferation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Cell Cycle Neuroendocrine Cell Differentiation
Pathways		ABC-family proteins mediated transport Abacavir transmembrane transport Abacavir transport and metabolism
Drugs		Adenosine triphosphate Roxithromycin Voacamine
Diseases
GWAS
Protein-Protein Interactions		10 interactors: BCCIP CAV1 CD4 HAX1 LNX1 MAPKAP1 MAPRE1 PIM1 PSMB8 RNF2	13 interactors: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B FAM46A HIST1H2BN ITSN2 PTN RAD51 RPL23
Entrez ID		5243	56647
HPRD ID		01370	16542
Ensembl ID		ENSG00000085563	ENSG00000107949
Uniprot IDs		A4D1D2 P08183	B4DUS0 B4E318 Q9P287
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of T Cell Activation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Cell Cycle Positive Regulation Of Cell-cell Adhesion Mitotic Cell Cycle Phase Transition Positive Regulation Of Protein Phosphorylation Cell Cycle Phase Transition Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of T Cell Activation Regulation Of Kinase Activity Positive Regulation Of Cell Activation Positive Regulation Of Phosphorylation Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Lymphocyte Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Ubiquitination Regulation Of Cell Activation Nitric Oxide Homeostasis Histone H2A-K119 Monoubiquitination Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Positive Regulation Of Microtubule Plus-end Binding Regulation Of Inward Rectifier Potassium Channel Activity Positive Regulation Of Signal Transduction Viral Process Positive Regulation Of Transferase Activity Regulation Of Immune System Process	Cell Cycle Response To Ionizing Radiation Cell Cycle Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Ionizing Radiation Cellular Response To DNA Damage Stimulus Cell Aging Double-strand Break Repair Via Homologous Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Recombinational Repair Signal Transduction In Response To DNA Damage Negative Regulation Of MRNA 3'-end Processing Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Meiosis I DNA-dependent DNA Replication Signal Transduction By P53 Class Mediator Positive Regulation Of DNA Ligation Cellular Response To Camptothecin G2/M Transition Of Mitotic Cell Cycle Response To Camptothecin Response To UV Cellular Response To Radiation Cell Cycle Arrest DNA Recombinase Assembly Intestinal Epithelial Cell Maturation Double-strand Break Repair Cell Maturation DNA Repair Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Filopodium Assembly Xenobiotic Transport Protein-DNA Complex Assembly Meiotic Nuclear Division Negative Regulation Of Protein Export From Nucleus Cellular Macromolecular Complex Assembly Positive Regulation Of Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Protein K6-linked Ubiquitination Cellular Response To UV-B Replication Fork Protection Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Proliferation Adiponectin-activated Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Ribosomal Protein Import Into Nucleus Regulation Of Cell Proliferation Meiotic Cell Cycle
Tagcloud ?		abcg2 arg72pro arg952lys asp1853asn atm atp7b backgroundovarian chances conclusionsthe emphasized facts gstm1 gstp1 gstt1 ile1145 inverted mark mark0 methodsin pgr question resultsten ser406ala ser894ala underscore unfavorable val660leu xenobiotics	abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Difference) ?		abcg2 arg72pro arg952lys asp1853asn atm atp7b backgroundovarian chances conclusionsthe emphasized facts gstm1 gstp1 gstt1 ile1145 inverted mark mark0 methodsin pgr question resultsten ser406ala ser894ala underscore unfavorable val660leu xenobiotics	abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Intersection) ?