PGM1 and S100A1

Number of citations of the paper that reports this interaction (PMID 8894274)
7

Data Source:
HPRD (in vitro)

		PGM1	S100A1
Gene Name		phosphoglucomutase 1	S100 calcium binding protein A1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Actin Cytoskeleton Extracellular Vesicular Exosome	Nucleus Sarcoplasmic Reticulum Z Disc M Band Neuron Projection Protein Complex
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Galactose Catabolic Process Small Molecule Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity
Pathways		Glucose metabolism Galactose catabolism Glycogen synthesis Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs			Olopatadine
Diseases
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Type 1 diabetes ( 19430480)
Protein-Protein Interactions		9 interactors: APP PAXIP1 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	24 interactors: ACTA1 AGER ANXA6 ATP2A2 CACYBP CAPZA1 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		5236	6271
HPRD ID		01389	01489
Ensembl ID		ENSG00000079739	ENSG00000160678
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	P23297
PDB IDs			2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Regulation Of Chromosome Organization Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process RNA-dependent DNA Replication Negative Regulation Of DNA Replication Negative Regulation Of Cellular Metabolic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Assembly Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Regulation Of Organelle Organization Positive Regulation Of Organelle Organization Regulation Of DNA Replication Regulation Of Telomerase Activity Chromosome Organization DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Component Organization Negative Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome Homeostatic Process DNA Replication Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of DNA Recombination Cellular Component Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Protein ADP-ribosylation Positive Regulation Of Voltage-gated Calcium Channel Activity Synaptic Growth At Neuromuscular Junction	Muscle System Process Response To Abiotic Stimulus Regulation Of Cardiac Muscle Cell Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Protein Complex Assembly Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Striated Muscle Contraction Glycogen Catabolic Process Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Polysaccharide Catabolic Process Calcium Ion Transport Relaxation Of Muscle Striated Muscle Tissue Development Negative Regulation Of Heart Contraction Skeletal Muscle Fiber Development Response To Hormone Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Metal Ion Muscle Tissue Development Cellular Component Assembly Myotube Cell Development Regulation Of Cellular Localization Cellular Carbohydrate Catabolic Process Regulation Of The Force Of Heart Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Response To Wounding Regulation Of Ion Homeostasis Regulation Of Actin Filament-based Process Cellular Metal Ion Homeostasis Cellular Response To Alkaloid Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Astrocyte Differentiation Cytosolic Calcium Ion Homeostasis Cellular Cation Homeostasis Actin-mediated Cell Contraction Cellular Ion Homeostasis Response To Peptide Hormone Cardiac Conduction Tissue Development Negative Regulation Of Striated Muscle Tissue Development Steroid Hormone Receptor Complex Assembly Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Positive Regulation Of Schwann Cell Proliferation
Tagcloud ?		1p34 4q11 arm autosomal began c8 chromosome decade excluded familial fifth fourth fsp globulin linkage located location loci locus lod middle p36 paraplegia pure q13 rh slow spastic varied	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Difference) ?		1p34 4q11 arm autosomal began c8 chromosome decade excluded familial fifth fourth fsp globulin linkage located location loci locus lod middle p36 paraplegia pure q13 rh slow spastic varied	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Intersection) ?