NDRG4 and CACFD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NDRG4	CACFD1
Description		NDRG family member 4	calcium channel flower domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Cell Projection Membrane	Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Synapse Recycling Endosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Heart Looping Signal Transduction Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Liver enzyme levels (alanine transaminase) ( 33972514) Oily fish consumption ( 32066663) Pork consumption ( 32066663) QT interval ( 19305408 19305409 22726844) Schizophrenia ( 29483656)	Gut microbiota (functional units) ( 27694959)
Interacting Genes		37 interacting genes: AGTRAP APLNR ARFIP2 ARL6IP1 ATP5PF BCL2L13 CACFD1 CDR1 CIDEB CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A	11 interacting genes: CREB3 HSFX1 HSFX2 LDAF1 MTERF3 NDRG4 PITPNC1 PNKP RBFA SH3GLB1 SNCA
Entrez ID		65009	11094
HPRD ID		14817	12974
Ensembl ID		ENSG00000103034	ENSG00000160325
Uniprot IDs		A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0	Q9UGQ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Synaptic Vesicle Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Formation Cytoplasmic Vesicle Endoplasmic Reticulum Tubular Network Membrane Organization Synaptic Vesicle Membrane Regulation Of Synaptic Vesicle Priming Protein Binding Regulation Of Short-term Neuronal Synaptic Plasticity Endoplasmic Reticulum Organization Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Membrane Organization	Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Mitochondrial Outer Membrane Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Fatty Acid Binding Positive Regulation Of Deacetylase Activity Protein Localization To Vacuolar Membrane
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