PFKL and KRTAP4-12

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PFKL	KRTAP4-12
Description		phosphofructokinase, liver type	keratin associated protein 4-12
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Nucleotide Binding Catalytic Activity 6-phosphofructokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	Protein Binding
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Negative Regulation Of Insulin Secretion Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis	Hair Cycle
Pathways		Neutrophil degranulation Glycolysis
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Rheumatoid arthritis ( 21505073)
Interacting Genes		18 interacting genes: APP ATN1 CEBPA COPS6 DNAAF5 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PFKM PRPF40A SHANK3 SUMO2 TESK1 TNFAIP3 USP39 YWHAQ	160 interacting genes: ADAM12 ADAMTSL4 ALPP AQP1 ATG12 ATN1 AXIN1 BAG4 BAHD1 BEX2 C10orf62 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CDX2 CHCHD3 CHIC2 CHRD CLCNKA CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 CYSRT1 DBF4B DLK2 EIF4E2 ELOA2 FAM107A FAM27E3 FAM76B FBXL18 FBXO34 FBXW5 FCHO1 FUCA2 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 IGSF8 ILF3 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-2 KRTAP4-4 KRTAP5-1 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NBPF19 NOTCH2NLA NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP POU4F2 PRKAB2 PRKAG1 PRR13 PTPMT1 QPRT R3HDM2 RERE RPS28 SHFL SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY1 SPRY2 TAP1 TBC1D16 TBC1D23 TGM1 THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF414 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF497 ZNF581 ZNF638 ZNF655 ZNF696 ZNF764 ZNF837 ZSCAN26
Entrez ID		5211	83755
HPRD ID		01385	13941
Ensembl ID		ENSG00000141959	ENSG00000213416
Uniprot IDs		P17858 Q7L2M7	Q9BQ66
PDB IDs		7LW1 8W2G 8W2H 8W2I 8W2J
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Interleukin-1 Production Regulation Of Tumor Necrosis Factor Production Amylin Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Toll Signaling Pathway Regulation Of Interleukin-6 Production Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Protein Catabolic Process Regulation Of Inflammatory Response Memory Cytosol Leukocyte Activation Involved In Inflammatory Response Identical Protein Binding Regulation Of Interleukin-1 Beta Production Kinase Binding Nuclear Matrix RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Intermediate Filament Regulation Of Toll-like Receptor 4 Signaling Pathway TIR Domain Binding Toll Binding ATP-dependent Histone Chaperone Activity Induced Systemic Resistance Phosphofructokinase Activity Glycolysis From Storage Polysaccharide Through Glucose-1-phosphate Tolerance Induction To Lipopolysaccharide Protein Modification By Small Protein Removal Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Macrophage Differentiation Positive Regulation Of Protein Localization Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Proteolysis Positive Regulation Of Defense Response	Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Identical Protein Binding
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