ATP5ME and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP5ME	CIDEB
Description		ATP synthase membrane subunit e	cell death inducing DFFA like effector b
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Protein-containing Complex Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		5 interacting genes: CIDEB ERBB3 FOS SMAD2 SPG21	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		521	27141
HPRD ID		03308	11981
Ensembl ID		ENSG00000169020	ENSG00000136305
Uniprot IDs		P56385	Q9UHD4
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	1D4B
Enriched GO Terms of Interacting Partners?		Enzyme-linked Receptor Protein Signaling Pathway SMAD Protein Signal Transduction R-SMAD Binding Response To Growth Factor Response To Epidermal Growth Factor Mesenchyme Development Epidermal Growth Factor Receptor Signaling Pathway Response To Transforming Growth Factor Beta ERBB Signaling Pathway Medium-term Memory Cellular Response To Prolactin Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Intracellular Signal Transduction Identical Protein Binding Double-stranded DNA Binding Homomeric SMAD Protein Complex Neuregulin Receptor Activity Cell Surface Receptor Signaling Pathway Response To Prolactin Conditioned Taste Aversion Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Signal Transduction Intracellular Signaling Cassette Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Mesoderm Morphogenesis Lipid Droplet Fusion Transcription Factor AP-1 Complex Cellular Response To Zinc Ion Starvation Pericardium Development Schwann Cell Differentiation Transcription Regulator Complex Response To Gravity Odontoblast Differentiation SMAD Protein Complex Trophoblast Cell Migration Response To Alcohol Heteromeric SMAD Protein Complex Heart Development ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Determination Of Left/right Asymmetry In Lateral Mesoderm	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
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