KDM3B and SPAG8

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		KDM3B	SPAG8
Gene Name		lysine (K)-specific demethylase 3B	sperm associated antigen 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Acrosomal Vesicle Nucleus Membrane
	Molecular Function	Metal Ion Binding Dioxygenase Activity	Molecular_function Microtubule Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Oxidation-reduction Process	Biological_process Positive Regulation Of Protein Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Chromatin modifying enzymes Chromatin organization HDMs demethylate histones
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		4 interactors: CREBBP HIST3H3 SPAG8 ZNF512B	15 interactors: CARM1 CSTF2 DTX2 JMJD4 KDM3B KLHL32 NEDD4L PITX1 PRMT1 PRMT2 PRMT5 RAN SNRPC UBQLN4 WHSC1L1
Entrez ID		51780	26206
HPRD ID		11055	12039
Ensembl ID		ENSG00000120733	ENSG00000137098
Uniprot IDs		Q7LBC6	Q99932
PDB IDs
Enriched GO Terms of Interacting Partners?			Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Methylation Chromatin Modification Chromatin Organization Histone Modification Methylation Chromosome Organization Gene Expression Histone H4-R3 Methylation Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Peptidyl-amino Acid Modification Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nitrogen Compound Metabolic Process Organelle Organization Histone H3-R17 Methylation Cellular Protein Modification Process Ribonucleoprotein Complex Biogenesis Intracellular Steroid Hormone Receptor Signaling Pathway RNA Splicing Regulation Of Metabolic Process Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Positive Regulation Of Caveolin-mediated Endocytosis Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Ribosomal Small Subunit Export From Nucleus Branchiomeric Skeletal Muscle Development MRNA 5'-splice Site Recognition Regulation Of Growth Plate Cartilage Chondrocyte Proliferation
Tagcloud ?		associates capturing causing demethylase depletes derepression drosophila gliomas h3k27m h3k9 h3k9m heterochromatic insight jhdm2 lysine methionine misregulation modifying nucleosomes perturbations polycomb prc2 reagents repressive resembles robust suppresses tools variegation	azoospermia bonferroni cgtg chinese conferred correction crem haplotype idiopathic iplex kif17b maturation noa nonobstructive played polymorphisms protective rs1148247 rs11592356 rs2295415 rs22954152 rs4934540 sequenom seventeen snps spermatogenesis tag tatg variants
Tagcloud (Difference) ?		associates capturing causing demethylase depletes derepression drosophila gliomas h3k27m h3k9 h3k9m heterochromatic insight jhdm2 lysine methionine misregulation modifying nucleosomes perturbations polycomb prc2 reagents repressive resembles robust suppresses tools variegation	azoospermia bonferroni cgtg chinese conferred correction crem haplotype idiopathic iplex kif17b maturation noa nonobstructive played polymorphisms protective rs1148247 rs11592356 rs2295415 rs22954152 rs4934540 sequenom seventeen snps spermatogenesis tag tatg variants
Tagcloud (Intersection) ?