ZNF775 and FES

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZNF775	FES
Gene Name		zinc finger protein 775	FES proto-oncogene, tyrosine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Golgi Apparatus Cytosol Focal Adhesion Microtubule Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	DNA Binding Metal Ion Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Immunoglobulin Receptor Binding Phosphatidylinositol Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Phosphorylation Chemotaxis Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Axon Guidance Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Cell Migration Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Positive Regulation Of Microtubule Polymerization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Regulation Of Mast Cell Degranulation Innate Immune Response Regulation Of Cell Differentiation Positive Regulation Of Myeloid Cell Differentiation Protein Autophosphorylation Regulation Of Vesicle-mediated Transport Regulation Of Cell Motility Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways		Generic Transcription Pathway	Signaling by SCF-KIT Axon guidance Semaphorin interactions Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling
Drugs
Diseases
GWAS			Blood pressure ( 21909110) Diastolic blood pressure ( 21909115) Hypertension ( 21909115) Systolic blood pressure ( 21909115)
Protein-Protein Interactions		6 interactors: FES MAPK6 OSGEP PPP2CB RPS6KA5 ZAK	31 interactors: BCAR1 BCR CSF2RB DOK1 DPYSL5 EGFR FKBP4 FKBP5 HSH2D HSPA4 IL4R IRS1 IRS2 JAK1 JAK2 JAK3 MDFI NEDD4 PDE4DIP PIK3R1 PLXNA1 POT1 PPID PTGES3 RASA1 RASA3 STAT3 TERF1 TRIM28 ZNF746 ZNF775
Entrez ID		285971	2242
HPRD ID		14567	01814
Ensembl ID		ENSG00000196456	ENSG00000182511
Uniprot IDs		Q96BV0	P07332
PDB IDs			1WQU 2DCR 3BKB 3CBL 3CD3 4DYL 4E93
Enriched GO Terms of Interacting Partners?		MAPK Cascade Signal Transduction By Phosphorylation Protein Phosphorylation Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Histone H2A-S1 Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Threonylcarbamoyladenosine Biosynthetic Process Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Histone H3-S10 Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Cellular Protein Metabolic Process Positive Regulation Of Histone Phosphorylation Threonylcarbamoyladenosine Metabolic Process Histone H3-S28 Phosphorylation Signal Transduction Protein Metabolic Process Positive Regulation Of Microtubule Polymerization Signaling Positive Regulation Of Actin Cytoskeleton Reorganization Adenosine Metabolic Process Axon Guidance Cell Communication Positive Regulation Of Organelle Organization Cellular Response To Stress Interleukin-1-mediated Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Response To Stress Positive Regulation Of Histone Acetylation Histone-serine Phosphorylation Positive Regulation Of Peptidyl-lysine Acetylation Cellular Metabolic Process Positive Regulation Of Protein Acetylation Regulation Of Mast Cell Degranulation Axonogenesis Regulation Of Microtubule Polymerization Cellular Response To Stimulus Intracellular Signal Transduction Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Response To Growth Factor Regulation Of Mast Cell Activation Peptidyl-tyrosine Autophosphorylation Activation Of JUN Kinase Activity	Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Response To Growth Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Organonitrogen Compound Cellular Response To Peptide JAK-STAT Cascade Positive Regulation Of Transport Intracellular Signal Transduction Cellular Response To Hormone Stimulus Regulation Of Cellular Localization Regulation Of Cell Migration Signal Transduction Regulation Of Protein Transport Regulation Of Cell Motility Regulation Of Immune Response Response To Peptide Hormone Cellular Response To Stimulus Response To Organic Substance Regulation Of Establishment Of Protein Localization Regulation Of Locomotion Response To Peptide Regulation Of Cellular Component Movement Response To Stimulus Response To Hormone Positive Regulation Of Protein Transport Cellular Response To Organic Substance Signaling Regulation Of Cell Death Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Cell Communication Neurotrophin Signaling Pathway Regulation Of Protein Localization Response To Organonitrogen Compound Response To Stress Cytokine-mediated Signaling Pathway Chaperone-mediated Protein Folding Insulin Receptor Signaling Pathway Protein Import Epidermal Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification ERBB Signaling Pathway Locomotion
Tagcloud ?			1d4 counterpart e1c3 electrophoretic epsilon germline heavy hela iepsilon immunoglobulin initiating irs jak1 jak3 lysates mediating mobility parental promotor pronounced radiolabeled reconstitution restored shift stat6 tyrosine undergo utilized utilizing
Tagcloud (Difference) ?			1d4 counterpart e1c3 electrophoretic epsilon germline heavy hela iepsilon immunoglobulin initiating irs jak1 jak3 lysates mediating mobility parental promotor pronounced radiolabeled reconstitution restored shift stat6 tyrosine undergo utilized utilizing
Tagcloud (Intersection) ?