INO80B and SOX13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		INO80B	SOX13
Description		INO80 complex subunit B	SRY-box transcription factor 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body Ino80 Complex	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Positive Regulation Of Telomere Maintenance In Response To DNA Damage	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Spinal Cord Oligodendrocyte Cell Differentiation Cell Differentiation Gamma-delta T Cell Differentiation Cell Fate Commitment Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)	Adverse response to drug ( 30420678) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ziprazidone in schizophrenia ( 29503163) Thyroid stimulating hormone levels ( 30843173)
Interacting Genes		64 interacting genes: ABI2 BANP BOLL CARD9 CAVIN1 CCDC85B CD81 CDR2L CEP70 CSNK2B CYSRT1 DPPA4 DVL3 E2F6 FLACC1 GOLGA6L9 GPRASP3 HMBOX1 HMGXB4 HOMEZ HOXA1 HSF2BP IGFBP2 KCTD7 KRT34 KRT40 KRTAP10-8 KRTAP12-2 KRTAP19-1 KRTAP6-2 LHX4 LIMS1 LZTS2 MID2 MKRN3 MORN3 MTUS2 MYLIP NBPF19 NOTCH2NLA PICK1 PIP4K2B PLAGL2 PNMA1 PNMA2 RBM39 RIMBP3C SOX13 SSX2IP STAC3 THAP1 TLE5 TNS2 TRAF2 TRIB3 TRIM27 TSPYL2 U2AF2 UIMC1 USH1G YAF2 ZNF526 ZNF552 ZRANB1	8 interacting genes: INO80B MECOM SMAD7 TRAF2 TXLNB VEZF1 YTHDC1 ZNF587
Entrez ID		83444	9580
HPRD ID		17110	09205
Ensembl ID		ENSG00000115274	ENSG00000143842
Uniprot IDs		Q9C086	Q9UN79
PDB IDs		6HTS 7ZI4
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Intermediate Filament	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of T Cell Cytokine Production Regulation Of DNA-templated Transcription Zinc Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Positive Regulation Of Chondrocyte Development Regulation Of T Cell Mediated Immunity TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Primary Follicle Stage Mammalian Oogenesis Stage Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Cytokine Production Involved In Immune Response Protein-containing Complex Disassembly Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex MRNA Alternative Polyadenylation Regulation Of JNK Cascade Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Chondrocyte Proliferation CD27 Signaling Pathway Nucleoplasm Chromatin Remodeling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone H3K9 Monomethyltransferase Activity Activin Receptor Binding Regulation Of Chondrocyte Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Regulation Of Metabolic Process Histone H3K9me2 Methyltransferase Activity Regulation Of Production Of Molecular Mediator Of Immune Response Heteromeric SMAD Protein Complex Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Histone H3K9 Methyltransferase Activity Regulation Of Adaptive Immune Response Thioesterase Binding
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