CYB5R1 and TTC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB5R1	TTC1
Description		cytochrome b5 reductase 1	tetratricopeptide repeat domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Platelet Alpha Granule Membrane Extracellular Exosome	Cytoplasm Peroxisomal Membrane Cytosol
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding Oxidoreductase Activity FAD Binding	Protein Binding Protein-macromolecule Adaptor Activity Unfolded Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Bicarbonate Transport Sterol Biosynthetic Process	Protein Folding Inflammatory Response Positive Regulation Of Inflammatory Response Chemokine-mediated Signaling Pathway Positive Regulation Of Neuroinflammatory Response
Pathways		Platelet degranulation Erythrocytes take up carbon dioxide and release oxygen
Drugs		Flavin adenine dinucleotide
Diseases
GWAS			Diastolic blood pressure ( 27841878) Hemoglobin levels ( 32327693) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		8 interacting genes: CYCS HIGD1C SGTA SGTB SLC51B TTC1 UBQLN1 UBQLN4	19 interacting genes: ACY1 CRY2 CYB5R1 GNA15 GNAI2 GNAQ GNAS HRAS HSPA1A HSPA4 HSPA8 NDE1 PSTPIP1 RNF41 SH3BP4 SOX5 SPP1 SREBF2 TGFBR1
Entrez ID		51706	7265
HPRD ID		06434	11881
Ensembl ID		ENSG00000159348	ENSG00000113312
Uniprot IDs		Q9UHQ9	Q99614
PDB IDs
Enriched GO Terms of Interacting Partners?		TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Protein Targeting To Membrane Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Protein Catabolic Process Regulation Of Proteolysis Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Nuclear Proteasome Complex Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Apoptosome Negative Regulation Of Autophagosome Maturation Regulation Of Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process BAT3 Complex Binding Positive Regulation Of Protein Glycosylation Cytosolic Proteasome Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Molecular Adaptor Activity Negative Regulation Of ERAD Pathway Regulation Of Protein Metabolic Process Bile Acid Secretion Regulation Of Protein Glycosylation Regulation Of Macroautophagy Positive Regulation Of Proteolysis Establishment Of Protein Localization To Membrane Protein Targeting Positive Regulation Of Protein Catabolic Process Protein-containing Complex Bile Acid Transmembrane Transporter Activity Mitochondrial Electron Transport, Ubiquinol To Cytochrome C K48-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Exit From Endoplasmic Reticulum Mitochondrial Respirasome Assembly Positive Regulation Of Protein Metabolic Process Response To Endoplasmic Reticulum Stress Identical Protein Binding Regulation Of Toll-like Receptor 3 Signaling Pathway Aggrephagy Response To Stress	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Receptor Binding Heterotrimeric G-protein Complex G Protein-coupled Acetylcholine Receptor Signaling Pathway Nucleotide Binding ATP-dependent Protein Folding Chaperone C3HC4-type RING Finger Domain Binding Acetylcholine Receptor Signaling Pathway Extracellular Exosome GTPase Activity Postsynaptic Signal Transduction ATP-dependent Protein Disaggregase Activity GTP Binding Response To Hormone Regulation Of Cell Communication Regulation Of Signaling G Protein Activity Signal Transduction Perinuclear Region Of Cytoplasm Negative Regulation Of Growth Regulation Of Signal Transduction Response To Unfolded Protein Response To Lipid Cellular Response To Laminar Fluid Shear Stress Cellular Response To Acidic PH Response To Laminar Fluid Shear Stress Chaperone-mediated Protein Complex Assembly Response To Acidic PH Cellular Response To PH Response To Prostaglandin E Regulation Of Growth Protein Refolding Entrainment Of Circadian Clock Regulation Of Multicellular Organismal Process Regulation Of Lipid Transport Cellular Response To Fluid Shear Stress Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Negative Regulation Of Lipid Transport Negative Regulation Of Cell Growth FAD Binding Response To PH Regulation Of Cell Growth Cytosol Photoreactive Repair Regulation Of Transport Response To Fluid Shear Stress Negative Regulation Of Cell Population Proliferation Chaperone-mediated Autophagy Translocation Complex Disassembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?