TTC1

Description		tetratricopeptide repeat domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Membrane Cytosol
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Unfolded Protein Binding
	Biological Process	Protein Folding Inflammatory Response Positive Regulation Of Inflammatory Response Chemokine-mediated Signaling Pathway Positive Regulation Of Neuroinflammatory Response
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Hemoglobin levels ( 32327693) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		19 interacting genes: ACY1 CRY2 CYB5R1 GNA15 GNAI2 GNAQ GNAS HRAS HSPA1A HSPA4 HSPA8 NDE1 PSTPIP1 RNF41 SH3BP4 SOX5 SPP1 SREBF2 TGFBR1
Entrez ID		7265
HPRD ID		11881
Ensembl ID		ENSG00000113312
Uniprot IDs		Q99614
PDB IDs
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Receptor Binding Heterotrimeric G-protein Complex G Protein-coupled Acetylcholine Receptor Signaling Pathway Nucleotide Binding ATP-dependent Protein Folding Chaperone C3HC4-type RING Finger Domain Binding Acetylcholine Receptor Signaling Pathway Extracellular Exosome GTPase Activity Postsynaptic Signal Transduction ATP-dependent Protein Disaggregase Activity GTP Binding Response To Hormone Regulation Of Cell Communication Regulation Of Signaling G Protein Activity Signal Transduction Perinuclear Region Of Cytoplasm Negative Regulation Of Growth Regulation Of Signal Transduction Response To Unfolded Protein Response To Lipid Cellular Response To Laminar Fluid Shear Stress Cellular Response To Acidic PH Response To Laminar Fluid Shear Stress Chaperone-mediated Protein Complex Assembly Response To Acidic PH Cellular Response To PH Response To Prostaglandin E Regulation Of Growth Protein Refolding Entrainment Of Circadian Clock Regulation Of Multicellular Organismal Process Regulation Of Lipid Transport Cellular Response To Fluid Shear Stress Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Negative Regulation Of Lipid Transport Negative Regulation Of Cell Growth FAD Binding Response To PH Regulation Of Cell Growth Cytosol Photoreactive Repair Regulation Of Transport Response To Fluid Shear Stress Negative Regulation Of Cell Population Proliferation Chaperone-mediated Autophagy Translocation Complex Disassembly
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