CYB5R1

Description		cytochrome b5 reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Platelet Alpha Granule Membrane Extracellular Exosome
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding Oxidoreductase Activity FAD Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Bicarbonate Transport Sterol Biosynthetic Process
Pathways		Platelet degranulation Erythrocytes take up carbon dioxide and release oxygen
Drugs		Flavin adenine dinucleotide
Diseases
GWAS
Interacting Genes		8 interacting genes: CYCS HIGD1C SGTA SGTB SLC51B TTC1 UBQLN1 UBQLN4
Entrez ID		51706
HPRD ID		06434
Ensembl ID		ENSG00000159348
Uniprot IDs		Q9UHQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Protein Targeting To Membrane Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Protein Catabolic Process Regulation Of Proteolysis Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Nuclear Proteasome Complex Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Apoptosome Negative Regulation Of Autophagosome Maturation Regulation Of Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process BAT3 Complex Binding Positive Regulation Of Protein Glycosylation Cytosolic Proteasome Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Molecular Adaptor Activity Negative Regulation Of ERAD Pathway Regulation Of Protein Metabolic Process Bile Acid Secretion Regulation Of Protein Glycosylation Regulation Of Macroautophagy Positive Regulation Of Proteolysis Establishment Of Protein Localization To Membrane Protein Targeting Positive Regulation Of Protein Catabolic Process Protein-containing Complex Bile Acid Transmembrane Transporter Activity Mitochondrial Electron Transport, Ubiquinol To Cytochrome C K48-linked Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Exit From Endoplasmic Reticulum Mitochondrial Respirasome Assembly Positive Regulation Of Protein Metabolic Process Response To Endoplasmic Reticulum Stress Identical Protein Binding Regulation Of Toll-like Receptor 3 Signaling Pathway Aggrephagy Response To Stress
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