GET4 and SNCAIP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GET4	SNCAIP
Gene Name		golgi to ER traffic protein 4 homolog (S. cerevisiae)	synuclein, alpha interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol BAT3 Complex	Cytoplasm Synaptic Vesicle Presynaptic Membrane Neuronal Cell Body
	Molecular Function		Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Transport Tail-anchored Membrane Protein Insertion Into ER Membrane	Dopamine Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ATP5H CAPNS1 CDKN1A EEF1G KAT5 KIAA1377 KIFC2 PLK1 PRKAB2 PRKCSH PTMS SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	19 interactors: AES AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PARK2 PINK1 PPHLN1 PPP1CA PTN RNF19A SEPT4 SH2D3C SIAH1 SIAH2 SNCA UBB
Entrez ID		51608	9627
HPRD ID		12909	04804
Ensembl ID		ENSG00000239857	ENSG00000064692
Uniprot IDs		Q7L5D6	Q9NVG1 Q9Y6H5
PDB IDs			2KES
Enriched GO Terms of Interacting Partners?		Response To Ionizing Radiation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Response To Hyperoxia Response To Radiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Energy Derivation By Oxidation Of Organic Compounds	Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Proteolysis Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Protein Ubiquitination Regulation Of Proteolysis Regulation Of Dopamine Secretion Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Dopamine Uptake Involved In Synaptic Transmission Modification-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Regulation Of Synaptic Vesicle Transport Regulation Of Signaling Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Mitochondrion Organization Positive Regulation Of Cellular Protein Metabolic Process Generation Of Precursor Metabolites And Energy Glycogen Metabolic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process
Tagcloud ?		anchored captured cascades details disassembled drive driving effectors energies ensure exemplified get3 gradients guided inputs machineries monitor ordered partners principles recycling requirement sequentially successive ta targeting unidentified vectorial	adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Difference) ?		anchored captured cascades details disassembled drive driving effectors energies ensure exemplified get3 gradients guided inputs machineries monitor ordered partners principles recycling requirement sequentially successive ta targeting unidentified vectorial	adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Intersection) ?