GET4 and SOD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		GET4	SOD2
Gene Name		golgi to ER traffic protein 4 homolog (S. cerevisiae)	superoxide dismutase 2, mitochondrial
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol BAT3 Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome
	Molecular Function		DNA Binding Superoxide Dismutase Activity Oxygen Binding Manganese Ion Binding Identical Protein Binding
	Biological Process	Transport Tail-anchored Membrane Protein Insertion Into ER Membrane	Response To Reactive Oxygen Species Response To Superoxide Age-dependent Response To Reactive Oxygen Species Response To Hypoxia Release Of Cytochrome C From Mitochondria Liver Development Detection Of Oxygen Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Transcription From RNA Polymerase II Promoter Glutathione Metabolic Process Superoxide Metabolic Process Heart Development Locomotory Behavior Regulation Of Blood Pressure Negative Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Cold Post-embryonic Development Response To Manganese Ion Response To Zinc Ion Response To Selenium Ion Response To Gamma Radiation Response To Activity Removal Of Superoxide Radicals Respiratory Electron Transport Chain Hemopoiesis Oxygen Homeostasis Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Silicon Dioxide Response To Isolation Stress Response To Immobilization Stress Response To Drug Response To Hydrogen Peroxide Superoxide Anion Generation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Fat Cell Differentiation Response To Cadmium Ion Negative Regulation Of Fibroblast Proliferation Neuron Development Response To Axon Injury Erythrophore Differentiation Hydrogen Peroxide Biosynthetic Process Regulation Of Catalytic Activity Protein Homotetramerization Response To Electrical Stimulus Regulation Of Mitochondrial Membrane Potential Iron Ion Homeostasis Response To Hyperoxia Response To Magnetism Cellular Response To Ethanol Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Age-related macular degeneration (GA) ( 22705344)
Protein-Protein Interactions		17 interactors: ATP5H CAPNS1 CDKN1A EEF1G KAT5 KIAA1377 KIFC2 PLK1 PRKAB2 PRKCSH PTMS SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	8 interactors: APP CYP4F12 GET4 HDHD2 KIAA1549 NOL12 RAB4A RPS3A
Entrez ID		51608	6648
HPRD ID		12909	00938
Ensembl ID		ENSG00000239857	ENSG00000112096
Uniprot IDs		Q7L5D6	P04179
PDB IDs			1AP5 1AP6 1EM1 1JA8 1LUV 1LUW 1MSD 1N0J 1N0N 1PL4 1PM9 1QNM 1SZX 1VAR 1XDC 1XIL 1ZSP 1ZTE 1ZUQ 2ADP 2ADQ 2GDS 2P4K 2QKA 2QKC 3C3S 3C3T
Enriched GO Terms of Interacting Partners?		Response To Ionizing Radiation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Response To Hyperoxia Response To Radiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Energy Derivation By Oxidation Of Organic Compounds	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Pressure Natriuresis Vitamin K Biosynthetic Process Membrane Organization Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Cellular Localization Establishment Of Protein Localization To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Vitamin K Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Long-chain Fatty Acid Catabolic Process Protein Insertion Into ER Membrane Neuron Remodeling Cellular Protein Localization Protein Localization To Membrane
Tagcloud ?		anchored captured cascades details disassembled drive driving effectors energies ensure exemplified get3 gradients guided inputs machineries monitor ordered partners principles recycling requirement sequentially successive ta targeting unidentified vectorial	arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider
Tagcloud (Difference) ?		anchored captured cascades details disassembled drive driving effectors energies ensure exemplified get3 gradients guided inputs machineries monitor ordered partners principles recycling requirement sequentially successive ta targeting unidentified vectorial	arbitrary biogenesis catalase centrally damages dihydroethidium dw femoral hypoperfusion iliac ligatures methoxyisobutylisonitrile mibi mimicking minute mmol muscles myopathic paramagnetic pgc proliferator respiration rounded scintigraphic scintigraphies submitted swiss vmax wider
Tagcloud (Intersection) ?