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PDHA1 and PDK3
Number of citations of the paper that reports this interaction (PMID
12676647
)
68
Data Source:
HPRD
(in vitro)
PDHA1
PDK3
Gene Name
pyruvate dehydrogenase (lipoamide) alpha 1
pyruvate dehydrogenase kinase, isozyme 3
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Mitochondrion
Mitochondrial Matrix
Pyruvate Dehydrogenase Complex
Mitochondrion
Mitochondrial Matrix
Molecular Function
Pyruvate Dehydrogenase Activity
Pyruvate Dehydrogenase (acetyl-transferring) Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity
Protein Binding
ATP Binding
Biological Process
Glucose Metabolic Process
Acetyl-CoA Biosynthetic Process From Pyruvate
Pyruvate Metabolic Process
Glycolytic Process
Tricarboxylic Acid Cycle
Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
Cellular Metabolic Process
Small Molecule Metabolic Process
Glucose Metabolic Process
Pyruvate Metabolic Process
Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
Regulation Of Glucose Metabolic Process
Peptidyl-serine Phosphorylation
Peroxisome Proliferator Activated Receptor Signaling Pathway
Cellular Metabolic Process
Small Molecule Metabolic Process
Cellular Response To Glucose Stimulus
Cellular Response To Fatty Acid
Hypoxia-inducible Factor-1alpha Signaling Pathway
Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Regulation of pyruvate dehydrogenase (PDH) complex
Pyruvate metabolism
Signaling by Retinoic Acid
Pyruvate metabolism and Citric Acid (TCA) cycle
The citric acid (TCA) cycle and respiratory electron transport
Regulation of pyruvate dehydrogenase (PDH) complex
Pyruvate metabolism
Signaling by Retinoic Acid
Pyruvate metabolism and Citric Acid (TCA) cycle
The citric acid (TCA) cycle and respiratory electron transport
Drugs
NADH
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
DLAT
EIF6
PDHB
PDK1
PDK2
PDK3
PDK4
PDP1
4 interactors:
APP
DLAT
EGFR
PDHA1
Entrez ID
5160
5165
HPRD ID
02420
03956
Ensembl ID
ENSG00000131828
ENSG00000067992
Uniprot IDs
P08559
Q15120
PDB IDs
1NI4
2OZL
3EXE
3EXF
3EXG
3EXH
3EXI
1Y8N
1Y8O
1Y8P
2PNR
2Q8I
Enriched GO Terms of Interacting Partners
?
Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
Regulation Of Acyl-CoA Biosynthetic Process
Regulation Of Fatty Acid Metabolic Process
Pyruvate Metabolic Process
Regulation Of Lipid Metabolic Process
Glucose Metabolic Process
Hexose Metabolic Process
Regulation Of Cellular Ketone Metabolic Process
Monosaccharide Metabolic Process
Monocarboxylic Acid Metabolic Process
Carboxylic Acid Metabolic Process
Organic Acid Metabolic Process
Regulation Of Glucose Metabolic Process
Regulation Of Phosphorus Metabolic Process
Hypoxia-inducible Factor-1alpha Signaling Pathway
Regulation Of Carbohydrate Metabolic Process
Carbohydrate Metabolic Process
Small Molecule Metabolic Process
Insulin Receptor Signaling Pathway
Glucose Homeostasis
Cellular Response To Insulin Stimulus
Tricarboxylic Acid Cycle
Response To Insulin
Cellular Response To Fatty Acid
Citrate Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Tricarboxylic Acid Metabolic Process
Aerobic Respiration
Regulation Of PH
Response To Fatty Acid
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Peptide
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Protein Phosphorylation
Cellular Response To Oxygen Levels
Acetyl-CoA Biosynthetic Process From Pyruvate
Cellular Response To Hormone Stimulus
Cellular Protein Metabolic Process
Cellular Response To Stress
Phosphate-containing Compound Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Metabolic Process
Cellular Respiration
Cellular Response To Acid Chemical
Cellular Response To Nutrient Levels
Intrinsic Apoptotic Signaling Pathway
Cellular Protein Modification Process
Regulation Of Cellular Ketone Metabolic Process
Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
Regulation Of Acyl-CoA Biosynthetic Process
Regulation Of Phosphorus Metabolic Process
Tricarboxylic Acid Cycle
Citrate Metabolic Process
Tricarboxylic Acid Metabolic Process
Aerobic Respiration
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Regulation Of Fatty Acid Metabolic Process
Pyruvate Metabolic Process
Alkanesulfonate Metabolic Process
Glucose Metabolic Process
Cellular Respiration
Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Synaptic Growth At Neuromuscular Junction
Astrocyte Activation
Hexose Metabolic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Collateral Sprouting In Absence Of Injury
Activation Of Phospholipase A2 Activity
Acetyl-CoA Biosynthetic Process From Pyruvate
Monosaccharide Metabolic Process
Learning Or Memory
Collateral Sprouting
Axon Midline Choice Point Recognition
Positive Regulation Of Phospholipase A2 Activity
Positive Regulation Of Cell Cycle
Cognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Response To Cobalamin
Response To UV-A
Regulation Of Lipid Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Axon Choice Point Recognition
Response To Hydroxyisoflavone
Response To Light Stimulus
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Superoxide Anion Generation
Acetyl-CoA Biosynthetic Process
Sulfur Compound Metabolic Process
Neuron Remodeling
Axon Guidance
Regulation Of Cellular Amino Acid Metabolic Process
Positive Regulation Of Catenin Import Into Nucleus
Regulation Of Mitotic Cell Cycle
Generation Of Precursor Metabolites And Energy
Response To Oxidative Stress
Regulation Of Phospholipase A2 Activity
Tagcloud
?
coffin
decalvans
dxs1052
dxs1053
dxs1195
dxs1229
dxs197
dxs207
dxs274
dxs365
dxs414
dxs418
dxs443
dxs451
dxs7101
dxs7161
dxs7592
dxs7593
dxs987
dxs989
dxs999
follicularis
kfsd
kqst80h1
lowry
retinoschisis
rp15
spinulosa
xlh
Tagcloud (Difference)
?
coffin
decalvans
dxs1052
dxs1053
dxs1195
dxs1229
dxs197
dxs207
dxs274
dxs365
dxs414
dxs418
dxs443
dxs451
dxs7101
dxs7161
dxs7592
dxs7593
dxs987
dxs989
dxs999
follicularis
kfsd
kqst80h1
lowry
retinoschisis
rp15
spinulosa
xlh
Tagcloud (Intersection)
?