GDE1 and RGS16

Number of citations of the paper that reports this interaction (PMID 10760272)
14

Data Source:
HPRD (in vitro, two hybrid)

		GDE1	RGS16
Gene Name		glycerophosphodiester phosphodiesterase 1	regulator of G-protein signaling 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Cytoplasm Plasma Membrane
	Molecular Function	Glycerophosphodiester Phosphodiesterase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity	GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Glycerol Metabolic Process Lipid Metabolic Process	Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CLGN RGS1 RGS16 RGS19 RGS2	14 interactors: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14
Entrez ID		51573	6004
HPRD ID		12070	03945
Ensembl ID		ENSG00000006007	ENSG00000143333
Uniprot IDs		Q9NZC3	O15492
PDB IDs			2BT2 2IK8
Enriched GO Terms of Interacting Partners?		Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Positive Regulation Of Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Binding Of Sperm To Zona Pellucida Brown Fat Cell Differentiation Sexual Reproduction Sperm-egg Recognition Regulation Of Smooth Muscle Contraction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell-cell Recognition Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Reproduction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction	Platelet Activation Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Positive Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Response To Stress Signal Transduction Peptidyl-tyrosine Autophosphorylation G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Protein Kinase Activity Cell Differentiation Positive Regulation Of Metabolic Process Cell Communication Regulation Of Kinase Activity Regulation Of Intracellular Transport Regulation Of ERK1 And ERK2 Cascade Response To Organonitrogen Compound Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Protein Autophosphorylation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Organ Development Neuron Development Central Nervous System Development Cellular Response To Stimulus Positive Regulation Of Phospholipase Activity T Cell Costimulation Positive Regulation Of Transferase Activity System Development Regulation Of Phospholipase Activity Regulation Of Protein Phosphorylation Neurogenesis Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lipase Activity Regulation Of MAPK Cascade Regulation Of MAP Kinase Activity Regulation Of Protein Transport Tissue Development Neuron Differentiation Regulation Of Establishment Of Protein Localization
Tagcloud ?		acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual	aspc bxpc candidates coexpressing cooperate cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb profiling rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38
Tagcloud (Difference) ?		acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual	aspc bxpc candidates coexpressing cooperate cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb profiling rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38
Tagcloud (Intersection) ?