GDE1

Description		glycerophosphodiester phosphodiesterase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Protein Binding Phosphoric Diester Hydrolase Activity Glycerophosphodiester Phosphodiesterase Activity Hydrolase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity
	Biological Process	Ethanolamine Metabolic Process Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Catabolic Process N-acylethanolamine Metabolic Process
Pathways		Glycerophospholipid catabolism
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: ADRA1A CLGN RGS1 RGS16 RGS19 RGS2 SLC10A1
Entrez ID		51573
HPRD ID		12070
Ensembl ID		ENSG00000006007
Uniprot IDs		Q9NZC3
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction GTPase Activity Positive Regulation Of Striated Muscle Contraction G-protein Alpha-subunit Binding Calmodulin Binding Positive Regulation Of Heart Contraction GTPase Activator Activity Positive Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Regulation Of Cardiac Muscle Hypertrophy Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Regulation Of Cardiac Muscle Contraction Positive Regulation Of GTPase Activity Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Striated Muscle Contraction Cytoplasmic Side Of Plasma Membrane Negative Regulation Of Glycine Import Across Plasma Membrane Positive Regulation Of Hydrolase Activity Response To Ethanol Pilomotor Reflex Alpha1-adrenergic Receptor Activity Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Signal Transduction Regulation Of GTPase Activity Membrane Leukotriene Signaling Pathway Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase Inhibitor Activity Plasma Membrane Regulation Of Muscle Contraction Neuron-glial Cell Signaling Bile Acid:sodium Symporter Activity Regulation Of The Force Of Heart Contraction By Chemical Signal Relaxation Of Vascular Associated Smooth Muscle Regulation Of Signal Transduction Regulation Of Heart Contraction Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Relaxation Of Smooth Muscle Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Action Potential Adrenergic Receptor Activity Bile Acid Transmembrane Transporter Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
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