GDE1 and RGS1

Number of citations of the paper that reports this interaction (PMID 10760272)
14

Data Source:
HPRD (two hybrid)

		GDE1	RGS1
Gene Name		glycerophosphodiester phosphodiesterase 1	regulator of G-protein signaling 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Cytoplasm Plasma Membrane
	Molecular Function	Glycerophosphodiester Phosphodiesterase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity	GTPase Activator Activity Calmodulin Binding
	Biological Process	Glycerol Metabolic Process Lipid Metabolic Process	Immune Response Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS			Celiac disease ( 20190752 18311140) Multiple sclerosis ( 21833088)
Protein-Protein Interactions		5 interactors: CLGN RGS1 RGS16 RGS19 RGS2	8 interactors: APP FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A
Entrez ID		51573	5996
HPRD ID		12070	15968
Ensembl ID		ENSG00000006007	ENSG00000090104
Uniprot IDs		Q9NZC3	Q08116
PDB IDs			2BV1 2GTP
Enriched GO Terms of Interacting Partners?		Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Positive Regulation Of Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Binding Of Sperm To Zona Pellucida Brown Fat Cell Differentiation Sexual Reproduction Sperm-egg Recognition Regulation Of Smooth Muscle Contraction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell-cell Recognition Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Reproduction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction
Tagcloud ?		acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual	aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular
Tagcloud (Difference) ?		acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual	aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular
Tagcloud (Intersection) ?