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PDE6H and COTL1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PDE6H
COTL1
Gene Name
phosphodiesterase 6H, cGMP-specific, cone, gamma
coactosin-like F-actin binding protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Nuclear Membrane
Extracellular Vesicular Exosome
Molecular Function
Enzyme Inhibitor Activity
CGMP Binding
3',5'-cyclic-GMP Phosphodiesterase Activity
Actin Binding
Protein Binding
Enzyme Binding
Biological Process
Activation Of MAPK Activity
Visual Perception
Metabolic Process
Negative Regulation Of Catalytic Activity
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Response To Stimulus
Biological_process
Defense Response To Fungus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
AGTR1
APP
COTL1
GNAO1
6 interactors:
ACTA1
ACTB
ACTG1
ALOX5
PDE6H
TERF2IP
Entrez ID
5149
23406
HPRD ID
03116
09482
Ensembl ID
ENSG00000139053
ENSG00000103187
Uniprot IDs
Q13956
Q14019
PDB IDs
1T2L
1T3X
1T3Y
1TMW
1VFQ
1WNJ
Enriched GO Terms of Interacting Partners
?
Phospholipase C-activating Angiotensin-activated Signaling Pathway
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Hydrolase Activity
Collateral Sprouting In Absence Of Injury
Positive Regulation Of NAD(P)H Oxidase Activity
Locomotory Behavior
Renin-angiotensin Regulation Of Aldosterone Production
Collateral Sprouting
Axon Midline Choice Point Recognition
Positive Regulation Of Phospholipase A2 Activity
Regulation Of Blood Vessel Size By Renin-angiotensin
Cellular Calcium Ion Homeostasis
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Calcium Ion Homeostasis
Positive Regulation Of Catalytic Activity
Axon Choice Point Recognition
Regulation Of NAD(P)H Oxidase Activity
Angiotensin-activated Signaling Pathway
Neuron Remodeling
Positive Regulation Of Cholesterol Esterification
Cellular Metal Ion Homeostasis
Response To External Stimulus
Regulation Of Cholesterol Esterification
Response To Oxidative Stress
Regulation Of Phospholipase A2 Activity
Low-density Lipoprotein Particle Remodeling
Cellular Cation Homeostasis
Forebrain Development
Regulation Of Blood Volume By Renin-angiotensin
Cellular Ion Homeostasis
Metal Ion Homeostasis
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway
Cellular Chemical Homeostasis
Cellular Copper Ion Homeostasis
Ion Homeostasis
Regulation Of Renal Sodium Excretion
Behavior
Chemotaxis
Copper Ion Homeostasis
Suckling Behavior
Regulation Of Catalytic Activity
Regulation Of Growth
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Regulation Of Excretion
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Plasma Lipoprotein Particle Remodeling
Defense Response To Fungus
Positive Regulation Of Steroid Metabolic Process
Cellular Homeostasis
Neuron Maturation
Platelet Aggregation
Retina Homeostasis
Myofibril Assembly
Adherens Junction Organization
Ephrin Receptor Signaling Pathway
Negative Regulation Of DNA Recombination At Telomere
Leukotriene Production Involved In Inflammatory Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Actomyosin Structure Organization
Skeletal Muscle Fiber Adaptation
Striated Muscle Cell Development
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Muscle Cell Development
Tissue Homeostasis
Platelet Activation
Cell Junction Assembly
Cell-cell Junction Organization
Protection From Non-homologous End Joining At Telomere
Striated Muscle Cell Differentiation
Telomere Capping
Protein Localization To Chromosome, Telomeric Region
Multicellular Organismal Homeostasis
Skeletal Muscle Thin Filament Assembly
Response To Stimulus
Phagocytosis
Lipoxin Metabolic Process
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Skeletal Myofibril Assembly
Skeletal Muscle Adaptation
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Muscle Cell Differentiation
Homotypic Cell-cell Adhesion
Defense Response
Lipoxygenase Pathway
Homeostatic Process
Regulation Of Double-strand Break Repair Via Homologous Recombination
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Organelle Organization
Axon Guidance
Movement Of Cell Or Subcellular Component
Blood Coagulation
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Hemostasis
Regulation Of Telomere Maintenance
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Response To Stress
Tagcloud
?
anxa2
biogenesis
breeding
cdna
chicken
chickens
coactosin
constructed
country
differentially
eef2
egg
excluding
glands
house
l2
laying
microarray
mx
ocx
overlapping
ovocalyxin
redundant
representing
semi
shell
sox18
taiwanese
transcripts
Tagcloud (Difference)
?
anxa2
biogenesis
breeding
cdna
chicken
chickens
coactosin
constructed
country
differentially
eef2
egg
excluding
glands
house
l2
laying
microarray
mx
ocx
overlapping
ovocalyxin
redundant
representing
semi
shell
sox18
taiwanese
transcripts
Tagcloud (Intersection)
?