EVL and APBB1IP

Number of citations of the paper that reports this interaction (PMID 15469846)
97

Data Source:
HPRD (in vivo)

		EVL	APBB1IP
Gene Name		Enah/Vasp-like	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding
	Biological Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Actin Polymerization Or Depolymerization Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Signal Transduction Blood Coagulation Platelet Activation
Pathways		TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Adaptive Immune System	p130Cas linkage to MAPK signaling for integrins Integrin alphaIIb beta3 signaling GRB2:SOS provides linkage to MAPK signaling for Integrins Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS			Inflammatory biomarkers ( 22228203) Response to angiotensin II receptor blocker therapy ( 22566498)
Protein-Protein Interactions		27 interactors: ABI1 ABI3 ABL1 APBB1 APBB1IP CRKL DNMBP FYB FYN HCK HTT LYN PFN2 POT1 PRPF40A SEMA6A SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 WAS WASL XIRP1 ZDHHC17	8 interactors: EVL GAS7 NDN PFN1 PRPF40A RAP1A VASP ZDHHC17
Entrez ID		51466	54518
HPRD ID		10942	16420
Ensembl ID		ENSG00000196405	ENSG00000077420
Uniprot IDs		Q9UI08	B4E100 Q7Z5R6
PDB IDs			3ZDL
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Axon Guidance Phagocytosis Fc Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Immune Response-regulating Signaling Pathway Regulation Of Organelle Organization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Process Chemotaxis Cell Projection Morphogenesis Cytoskeleton Organization Cell Part Morphogenesis Neuron Projection Morphogenesis Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Neuron Development Locomotion Cell Morphogenesis Involved In Differentiation Regulation Of Cytoskeleton Organization Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Neuron Projection Development Regulation Of Vesicle-mediated Transport Neuron Differentiation Cell Development Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cell Projection Organization Positive Regulation Of Organelle Organization Regulation Of Immune Response Actin Filament-based Process Negative Regulation Of Protein Complex Assembly Endocytosis Antigen Receptor-mediated Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Phosphorylation Anatomical Structure Morphogenesis Regulation Of Immune System Process Actin Filament Organization Organelle Organization	Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Cytoskeleton Organization Regulation Of Ruffle Assembly Nervous System Development Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Actin Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Neuron Projection Morphogenesis Actin Filament-based Process Generation Of Neurons Neurogenesis Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Stress Fiber Assembly Actin Filament Organization Cell Part Morphogenesis Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Cellular Component Biogenesis Cell Development Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Neuron Development Regulation Of Actin Cytoskeleton Organization Regulation Of Stress Fiber Assembly Protein Homotetramerization Cell Morphogenesis Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Differentiation Cell Projection Organization Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cytoskeleton Organization Protein Tetramerization Neural Tube Closure Axonogenesis System Development Regulation Of Cell Projection Assembly Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neural Tube Formation Response To Growth Factor
Tagcloud ?		adam29 cd109 cd248 cgh chl1 cladogram crcs csmd3 ercc6 ergic3 fbxw7 galns gnas iranian lgr mmp2 msi msp mss p2rx7 parsimony prkd1 ptprd rnf182 sfrs6 slc29a1 specifics syne1 tbx22
Tagcloud (Difference) ?		adam29 cd109 cd248 cgh chl1 cladogram crcs csmd3 ercc6 ergic3 fbxw7 galns gnas iranian lgr mmp2 msi msp mss p2rx7 parsimony prkd1 ptprd rnf182 sfrs6 slc29a1 specifics syne1 tbx22
Tagcloud (Intersection) ?