NFIL3 and MAFG

Number of citations of the paper that reports this interaction (PubMedID 23661758)
48

Data Source:
BioGRID (fluorescent resonance energy transfer)

		NFIL3	MAFG
Description		nuclear factor, interleukin 3 regulated	MAF bZIP transcription factor G
Image
GO Annotations	Cellular Component	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Natural Killer Cell Differentiation DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Immune Response Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Interleukin-4	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Adult Behavior Regulation Of Cell Population Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Nuclear events mediated by NFE2L2 NFE2L2 regulates pentose phosphate pathway genes Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) Birth weight ( 31043758) Inflammatory bowel disease ( 23128233) Offspring birth weight ( 31043758)
Interacting Genes		18 interacting genes: AMOTL2 BATF CFTR CREB3 DDIT3 DELEC1 DNMT3L DR1 FHL1 GMCL1 HSF2BP MAFF MAFG PDE9A PIH1D2 RINT1 TRAF2 UBR5	24 interacting genes: ATF3 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOMEZ HOXD12 MAF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM
Entrez ID		4783	4097
HPRD ID		05619	03605
Ensembl ID		ENSG00000165030	ENSG00000197063
Uniprot IDs		Q16649	O15525
PDB IDs		8K86 8K89 8K8A	7X5E 7X5F 7X5G
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Transcription Regulator Complex Integrated Stress Response Signaling CAMP Response Element Binding Protein Binding Response To Endoplasmic Reticulum Stress Cellular Response To Stress DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Male Meiosis I Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Ion Transport Intrinsic Apoptotic Signaling Pathway In Response To Nitrosative Stress Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress DNA Damage Response DNA-binding Transcription Factor Activity TORC2 Complex Disassembly Positive Regulation Of Deacetylase Activity Meiosis I Positive Regulation Of Gene Expression Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Regulation Of DNA-templated Transcription Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of DNA-templated Transcription Endoplasmic Reticulum Unfolded Protein Response CHOP-C/EBP Complex Negative Regulation Of Transcription By RNA Polymerase II CHOP-ATF4 Complex Intracellular Signal Transduction CHOP-ATF3 Complex Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Diaphragm Contraction Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Vascular Associated Smooth Muscle Cell Migration Negative Cofactor 2 Complex General Transcription Initiation Factor Activity Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Epidermis Development Sequence-specific Double-stranded DNA Binding Regulation Of Epidermal Cell Differentiation TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Meiosis I Cell Cycle Process	Chromatin RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Integrated Stress Response Signaling DNA Binding DNA-binding Transcription Factor Activity Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Stress Nucleoplasm Regulation Of Metabolic Process DNA-templated Transcription DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific CHOP-ATF3 Complex Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Astrocyte Differentiation Negative Regulation Of Biosynthetic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Metabolic Process Embryonic Morphogenesis Transcription Cis-regulatory Region Binding Cell Redox Homeostasis
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