TNFRSF12A and KRTAP3-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNFRSF12A	KRTAP3-3
Description		TNF receptor superfamily member 12A	keratin associated protein 3-3
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Plasma Membrane Cell Surface Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Angiogenesis Apoptotic Process Substrate-dependent Cell Migration, Cell Attachment To Substrate Cell Adhesion Cell Differentiation Positive Regulation Of Apoptotic Process Regulation Of Angiogenesis Positive Regulation Of Axon Extension Regulation Of Wound Healing Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Keratinization
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: KRTAP3-3 RAC1 SLC30A2 TNFSF12 TRAF1 TRAF2 TRAF3 TRAF5	78 interacting genes: ALDH3B1 ANAPC11 ARID5A ATG9A BEX2 CELF5 CERCAM CIMAP1B CTSZ CYSRT1 DCANP1 DCDC2B DMRT3 DOCK2 ERMAP FADS6 FAM168A FARS2 FOXC2 FOXH1 FOXP3 GNE GPS2 GSTP1 GUCD1 HOXA1 HR HYPK KLHL38 KRT83 KRTAP10-1 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP4-11 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-3 KRTAP9-8 LASP1 LCE1F LCE2B LCE3A LCE3C LCE3D LCE3E LCE4A LONRF1 LRRN4 MGAT5B MRPL23 MXD3 NR1D2 NTAQ1 NUFIP2 OLIG3 OTX1 P2RY6 PATZ1 PHLDA1 PITX1 PITX2 PLSCR3 PLSCR4 PRKAB2 PVR SHISA6 SMARCC1 SSC4D TNFRSF12A VENTX VGLL3 YPEL3 ZNF503
Entrez ID		51330	85293
HPRD ID		05801	13939
Ensembl ID		ENSG00000006327	ENSG00000212899
Uniprot IDs		Q9NP84	Q9BYR6
PDB IDs		2EQP 2KMZ 2RPJ
Enriched GO Terms of Interacting Partners?		Thioesterase Binding Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway CD40 Receptor Complex Signaling Adaptor Activity Regulation Of DNA-binding Transcription Factor Activity Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin Protein Ligase Binding Positive Regulation Of NF-kappaB Transcription Factor Activity CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Cytoplasmic Side Of Plasma Membrane Positive Regulation Of DNA-binding Transcription Factor Activity Apoptotic Process Cell Death Programmed Cell Death Cytokine-mediated Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Surface Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway TORC2 Complex Disassembly MRNA Stabilization Ubiquitin Protein Ligase Activity Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Identical Protein Binding Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Negative Regulation Of MRNA Catabolic Process RNA Stabilization Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Protein Kinase Binding Cerebral Cortex GABAergic Interneuron Development Regulation Of Intracellular Signal Transduction Protein Phosphatase Binding Negative Regulation Of RNA Catabolic Process TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of MRNA Metabolic Process Ubiquitin Ligase Complex Regulation Of Cell Communication	Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Hair Cycle Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Chromatin
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